Music clearance issues aside, this is a worthwhile purchase. "Daria" is a rather peculiar show when I saw it as a child. BECAUSE I was a child, I didn't get most of its highbrow colloquialisms conveyed as humor, and mostly laughed at when Daria's father, Jake, gets angry. Being older, I understood most of the jokes and I laughed at most of the season one episodes, which didn't happened to me before. It definitely works better as a mature show for a mature audience, and by that, I mean it's for smart people, not for something sinister to the gutterballs that this show makes fun of.
Seasons one and two were the strongest that the series has to offer in terms of humor and grounded storylines. Season three took a bizarre turn with surreal elements like the musical and humanized holidays, but it does have some good episodes. Season four takes a bit of the dramatic turn once a new character named Tom steps into the picture, which some fans of the show don't like but I personally don't mind him; this season also shattered Daria's sarcastic ego a bit. Her attitude had an even bigger change in the final season, to the point when she's started to rely on the very people she despised.
I like how much she has changed over the seasons, from being a non-conformist misanthrope to learning she's following the same patterns as the people she hates (although she still has that wonderful cynicism), making her less of a character type and more human. That's what I like about this show, people changing and learning about their state of beings. Most characters won't change, but by the end of the series, it's easy to see how far they have reached from the beginning, even if its subtle.
Moving on from the content itself to the technical aspects of the DVD. The extras are pretty worthless, although kudos for MTV having the two movies. They're packed in the same bonus disc, so they are continuity issues since "Is It Fall Yet" takes place after season four; also, it only has the edited version of "College" which is a bit of a letdown. It does have the Daria intros scattered across the first five DVDs, but they're set within the episode selection, and it doesn't indicate which episodes have the intros until an episode has been selected. The intros themselves are rather amusing, but worth seeing only once.
It's a DVD set that's worth it only by the content itself, and the content is strong. If you want a cartoon with a cerebral attitude and sarcastic charm, this is it.