Hi - There are some limitations and likely issues with this type of setup. Control Center can control a single TV with respect to power on/off and volume. That TV is defined and control is verified during setup. Changing the TV connected to control center after setup will likely cause loss of control issues. In addition, video formats are negotiated between the source device and the sink (display) device. Changing TVs in realtime with a switcher will likely have an impact on the success of that negotiation resulting in video issues and/or loss of signal. Encrypted shows with HDCP will likely fail as displaying an encrypted video on more than 1 display is in violation of HDCP.