Yes! I use it as a boot drive. I have both the Samsung and the Western digital on my Asus TUF Gaming X570 mother board. I’ve bench marked both, and they both run at comparable speeds; both are super duper fast...way way faster than a standard HDD drive and quite a bit faster than a standard 2.5 inch solid state drive.
I built my own desk top computer, and I decided I didn’t want any SATA drives and a lot of cables to hide and tuck away. My windows boot time with the Western Digital m.2 drive is fantastic...8 seconds or less. It would take my HDD drive 20 seconds to boot up and 40 to 50 seconds to shut down. Imagine! 8 seconds to boot up.
When I double click on an icon to open a program, it just opens now. Opening internet explorer...double click, and its instantly open. It takes less than 15 seconds to defragment where as on the HDD it would take 3-5 minutes.
Have fun with it. You likely won’t regret it. Also remember I have all new components...AMD Ryzen 7 3800X, GeForce RTX 2070 super, RAM is 3.2 ghz, and an ASUS TUF gaming X570 board which has two dedicated M.2 slots. I do game, and the M.2 hard drives make that a lot of fun.