Just to clarify for everyone- this is not a wine aerator, but is primarily designed to chemically remove sulfates from wine for those people who are sensitive to them. For those who find that red wine is a migraine trigger (like my wife, for example), the sulfites are a potential culprit. You do need to add a packet with the binding agent to the ullo for every bottle you wish to filter. These are about $20 for a six pack through their website, so figure it's going to cost you an extra $3.50 per bottle to use this thing. If it saves you a bad reaction, or allows you to enjoy a bottle of wine when you otherwise might have been afraid, that isn't too bad.
We used this on four bottles of wine (reds only, they are primarily what I drink, and those are the ones that seem to be problematic for my wife, so that is what we used. It can be used on whites and rose's, as well- but isn't recommended for sparkling wines) over the course of a week. (No, I don't normally drink four bottles of wine in a week... in case my mother is reading this). The wines ranged from a $7 bottle of Yellowtail shiraz to a $30 french cab franc. In addition to drinking the wine and waiting for side effects (the only way to determine if the ullo is providing benefit for you), I did make a point to do a test of filtered vs. unfiltered wine to determine if the process affected the taste/experience of the wine itself. Both glasses in this case were aerated with the ullo, with the latter being run through before the addition of the sulfite binding agent.
From the first bottle, the products flaw (to me) became apparent as it clearly altered the experience of the wine. I say experience, because it was more nuanced than just flavor (thought I found it did have some effect on flavor, as well, but in a very subtle way). It tended to smooth out the wine, rounding off tannins on those wines heavy with those, and altered the mouth feel to a different degree, as well. Everything that had been filtered seemed to lose complexity, but became more fruit forward in a way that may people may find pleasing. I personally don't want to do anything to my wine that alters its flavor in any way, at least for anything that I spent more than $10 on. I actually think it positively enhanced that $7 bottle of Yellowtail, however.
So- did it help? Well, after the first bottle, my wife got her migraine that night, per her routine. But we realized she was taste testing with both filtered and unfiltered wines, which exposed her to some sulfites, even if a much lower amount than usual. After that, she stuck to the filtered wines only, and had no headache whatsoever after all three of the remaining bottles. The epidemiologist in me is quick to admit that this sample is far to small to make any firm conclusions- but it gave us enough faith to order six more filters to use for those times in the future when my wife wants to indulge. We will just make sure to use it on those bottles where we (I) wouldn't be sad to see the nuances lost.