A:AnswerNo, a keyboard and mouse cannot be connected to the monitor itself. This monitor will work fine with most any PC or laptop that has HDMI, DVI or VGA connections.
A:AnswerThe base/neck can be removed, yes. Acer has not tested the monitor on an Apple product but it should work. You might post your question on the Acer Community where there are many users that post questions and offer help and advice on Acer products. The link is: https://community.acer.com/