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IF your desktop has Bluetooth capabilities, it should work just fine. A simple dongle to plug in is all you need to add Bluetooth, to your machine. Drivers SHOULDN'T be an issue.
Sorry, there was a problem. Please try again later.You can confidently use our mouse with your computer without any compatibility issues. If you have any further questions or need assistance with anything else, please feel free to ask. We're here to help! Carl | Insignia Support | https://www.bestbuy.com/site/best-buy-essentials-lightweight-bluetooth-optical-standard-ambidextrous-mouse-with-6-button-black/6453629.p?skuId=6453629
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