A:Answer Not one unit, but multiple units would work. Air purification is all about airflow. One unit wouldn't be able to clean the air in an entire home as there are things like walls, hallways, and doorways that block the airflow and therefore the particle from getting to the unit. When looking at units you'll want to be sure to look at the separate rooms you want to clean, I'd suggest the bedroom and a main living area, and then purchase the correct units for those room sizes. If you have more questions on choosing the proper unit(s), give us a call at 1-888-258-3247. We are available Monday - Friday, 8 am - 5 pm CST.