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Thanks for reaching out Reid. This PC should be compatible with both the AMD Ryzen 5 1600 and the Radeon RX 580. The only thing you may need to watch out for is to switch the drivers when you install the new parts onto your PC. You shouldn't need to upgrade the PSU, but just be aware of it. If you have any further questions or concerns then please do not hesitate to give our tech support agents a call for any assistance; we're always happy to help. Tech support: (888)937-5582 - CyberpowerPC Support
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