A:Answer It does "work" with MacOS. However, it will only move the cursor. Razer's software only works on Windows. You won't be able to use Razer Synapse, Cortex, or Axon. You won't be able to change the color of the lights from that machine. If you have a spare windows computer, you can program a profile to the mouse directly to use specific lighting effects & dpi, but that's about it.