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Best Buy customers often prefer the following products when searching for large hand gaming mouse.

A gaming mouse is a type of computer mouse that is designed for use with a variety of computer games. Gaming mice are often more specialized, and may feature extra programmable buttons, different ergonomic designs, or other features designed to improve gamers' experience. Browse the top-ranked list of large hand gaming mice below along with associated reviews and opinions.

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  1. Glorious - Model O Wired Optical Honeycomb RGB Gaming Mouse - Matte Black - Front_Zoom
    Top comment

    "A great buy if you have medium sized hands, or don't like ergonomic mice. Truly no qualms with the mouse itself....I had never heard of this brand. Tried it and it's hands down the best gaming mouse. Quality product....Best gaming mouse"

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    Product Description

    Model O’s Honeycomb Shell is the key to achieving a feather-light weight while maintaining its ultra-durable strength. You’ll barely feel the holes during gameplay, but they provide ventilation to keep your palms cool & fresh. Cleaning the Model O is easy, just use any air canister to keep your mouse good as new. Our braided cable is ultra-flexible and super lightweight, giving your mouse an almost wireless feel.
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    Top comment

    "A great buy if you have medium sized hands, or don't like ergonomic mice. Truly no qualms with the mouse itself....I had never heard of this brand. Tried it and it's hands down the best gaming mouse. Quality product....Best gaming mouse"

    See all customer reviews

    Product Description

    Model O’s Honeycomb Shell is the key to achieving a feather-light weight while maintaining its ultra-durable strength. You’ll barely feel the holes during gameplay, but they provide ventilation to keep your palms cool & fresh. Cleaning the Model O is easy, just use any air canister to keep your mouse good as new. Our braided cable is ultra-flexible and super lightweight, giving your mouse an almost wireless feel.
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    See all Gaming Mice
  2. Glorious - Model D Wireless Optical Honeycomb RGB Gaming Mouse - Matte Black - Front_Zoom
    Top comment

    "Awesome Mouse!...Hand placement is a bit odd but the rest is amazing!...Has to be one of the best gaming mouse for the price. The smoothness is sharp and it feels good in my hand."

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    Product Description

    The Model D Wireless prevents double-clicking and unresponsiveness, producing an unbelievably smooth operation. The proprietary BAMF Sensor redefines what is possible in a gaming mouse. Made in collaboration with Pixart, BAMF is optimized for unrivaled performance with a lower power draw - allowing you to game harder and longer than ever before. The sensor provides pinpoint precision with its 400 IPS tracking speed, 19,000 programmable DPI, and up to 1000 Hz polling rate. At a mere 69 grams, the Model D Wireless is light weight and utilizes a right-handed, ergonomic design that satisfyingly cradles your palm. The Model D Wireless comes with a flexible USB-C Ascended charging cable for nonstop performance when you need it most. The mouse allows for seamless operation in wired and wireless modes. Its honeycomb shell helps reduce weight while maintaining strength.
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    Top comment

    "Awesome Mouse!...Hand placement is a bit odd but the rest is amazing!...Has to be one of the best gaming mouse for the price. The smoothness is sharp and it feels good in my hand."

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    Product Description

    The Model D Wireless prevents double-clicking and unresponsiveness, producing an unbelievably smooth operation. The proprietary BAMF Sensor redefines what is possible in a gaming mouse. Made in collaboration with Pixart, BAMF is optimized for unrivaled performance with a lower power draw - allowing you to game harder and longer than ever before. The sensor provides pinpoint precision with its 400 IPS tracking speed, 19,000 programmable DPI, and up to 1000 Hz polling rate. At a mere 69 grams, the Model D Wireless is light weight and utilizes a right-handed, ergonomic design that satisfyingly cradles your palm. The Model D Wireless comes with a flexible USB-C Ascended charging cable for nonstop performance when you need it most. The mouse allows for seamless operation in wired and wireless modes. Its honeycomb shell helps reduce weight while maintaining strength.
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    See all Gaming Mice
  3. Glorious - Model D Wireless Optical Honeycomb RGB Gaming Mouse - Matte White - Front_Zoom
    Top comment

    "glorious mouse...great for large hands, affordable , sleeps and looks great...Gaming mouse...Very lightweight can barely tell it’s in your hand and battery life is outstanding"

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    Product Description

    The Model D Wireless prevents double-clicking and unresponsiveness, producing an unbelievably smooth operation. The proprietary BAMF Sensor redefines what is possible in a gaming mouse. Made in collaboration with Pixart, BAMF is optimized for unrivaled performance with a lower power draw - allowing you to game harder and longer than ever before. The sensor provides pinpoint precision with its 400 IPS tracking speed, 19,000 programmable DPI, and up to 1000 Hz polling rate. At a mere 69 grams, the Model D Wireless is light weight and utilizes a right-handed, ergonomic design that satisfyingly cradles your palm. Spend more time gaming with the Model D Wireless’ incredible 71* hours of play time on a single charge. (*Measured with RGB Off). D Wireless comes with a flexible USB-C Ascended charging cable for nonstop performance when you need it most. The mouse allows for seamless operation in wired and wireless modes. Its honeycomb shell helps reduce weight while maintaining strength. Easy to clean and also helps improve airflow while you game.
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    Top comment

    "glorious mouse...great for large hands, affordable , sleeps and looks great...Gaming mouse...Very lightweight can barely tell it’s in your hand and battery life is outstanding"

    See all customer reviews

    Product Description

    The Model D Wireless prevents double-clicking and unresponsiveness, producing an unbelievably smooth operation. The proprietary BAMF Sensor redefines what is possible in a gaming mouse. Made in collaboration with Pixart, BAMF is optimized for unrivaled performance with a lower power draw - allowing you to game harder and longer than ever before. The sensor provides pinpoint precision with its 400 IPS tracking speed, 19,000 programmable DPI, and up to 1000 Hz polling rate. At a mere 69 grams, the Model D Wireless is light weight and utilizes a right-handed, ergonomic design that satisfyingly cradles your palm. Spend more time gaming with the Model D Wireless’ incredible 71* hours of play time on a single charge. (*Measured with RGB Off). D Wireless comes with a flexible USB-C Ascended charging cable for nonstop performance when you need it most. The mouse allows for seamless operation in wired and wireless modes. Its honeycomb shell helps reduce weight while maintaining strength. Easy to clean and also helps improve airflow while you game.
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    See all Gaming Mice
  4. Logitech - G502 X LIGHTSPEED Wireless Gaming Mouse with HERO 25K Sensor - Black - Front_Zoom
    Top comment

    "amazing mouse but pricey...very expensive but very good. fit my hand perfectly...Great mouse for home/office needed something a little bigger for my hands which arent that big, but definitely prefer something i can grip rather than the generic small mice."

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    Product Description

    G502 X LIGHTSPEED, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor, reversible and removable DPI-shift button, redesigned scroll wheel with dual hyper-fast and precise ratchet modes, thin-wall molding and lightweight design, optimized battery lasting for up to 140 gaming hours, and more.
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    Top comment

    "amazing mouse but pricey...very expensive but very good. fit my hand perfectly...Great mouse for home/office needed something a little bigger for my hands which arent that big, but definitely prefer something i can grip rather than the generic small mice."

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    Product Description

    G502 X LIGHTSPEED, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor, reversible and removable DPI-shift button, redesigned scroll wheel with dual hyper-fast and precise ratchet modes, thin-wall molding and lightweight design, optimized battery lasting for up to 140 gaming hours, and more.
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    See all Gaming Mice
  5. Logitech - PRO X SUPERLIGHT Lightweight Wireless Optical Gaming Mouse with HERO 25K Sensor - Red - Front_Zoom
    Top comment

    "Gaming Mice...Good hand feel, very lightweight, battery life is amazing just overall great mice...A++++ mouse...If you have medium to large hands. This mouse is the perfect one. You wont wamt another mouse, unless they is a new version of this one."

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    Product Description

    Introducing PRO X SUPERLIGHT—one of our lightest, fastest PRO mouse ever. Powered by LIGHTSPEED, it’s here to help you remove all obstacles, so you can focus on nothing but winning. Get insanely precise, fast, and consistent control with HERO Sensor. Take first faster with zero-additive PTFE feet that deliver a dramatically smoother glide. Developed in collaboration with a large group of the world’s best esports pros, PRO X SUPERLIGHT features hyper-minimal design, but is packed with our latest technologies and advancements. PRO X SUPERLIGHT is available in black and white.
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    Top comment

    "Gaming Mice...Good hand feel, very lightweight, battery life is amazing just overall great mice...A++++ mouse...If you have medium to large hands. This mouse is the perfect one. You wont wamt another mouse, unless they is a new version of this one."

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    Product Description

    Introducing PRO X SUPERLIGHT—one of our lightest, fastest PRO mouse ever. Powered by LIGHTSPEED, it’s here to help you remove all obstacles, so you can focus on nothing but winning. Get insanely precise, fast, and consistent control with HERO Sensor. Take first faster with zero-additive PTFE feet that deliver a dramatically smoother glide. Developed in collaboration with a large group of the world’s best esports pros, PRO X SUPERLIGHT features hyper-minimal design, but is packed with our latest technologies and advancements. PRO X SUPERLIGHT is available in black and white.
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    See all Gaming Mice
  6. Razer - DeathAdder V3 Pro Lightweight Wireless Optical Gaming Mouse with 90 Hour Battery - White - Front_Zoom
    Top comment

    "Great mouse...Great light weight ergo mouse for large hands. Try and find the 4k dongle to pair with it!...A great option for large hands...Its lightweight and with included grip pads it really sticks into your hand. How it is a bid mouse. But if you have medium to large hands i find it very comfortable. "

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    Product Description

    With the Razer DeathAdder V3 Pro, victory takes on a new shape. Refined and reforged with the aid of top esports pros, its iconic ergonomic form is now more than 25% lighter than its predecessor, backed by a set of cutting-edge upgrades to push the limits of competitive play.
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    Top comment

    "Great mouse...Great light weight ergo mouse for large hands. Try and find the 4k dongle to pair with it!...A great option for large hands...Its lightweight and with included grip pads it really sticks into your hand. How it is a bid mouse. But if you have medium to large hands i find it very comfortable. "

    See all customer reviews

    Product Description

    With the Razer DeathAdder V3 Pro, victory takes on a new shape. Refined and reforged with the aid of top esports pros, its iconic ergonomic form is now more than 25% lighter than its predecessor, backed by a set of cutting-edge upgrades to push the limits of competitive play.
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    See all Gaming Mice
  7. Logitech - G502 X PLUS LIGHTSPEED Wireless Gaming Mouse with HERO 25K Sensor - White - Front_Zoom
    Top comment

    "The 502 is the best mouse hands down. All they did was make it wireless and better. ...Very comfortable if you have large hands, excellent battery life and very responsive."

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    Product Description

    G502 X PLUS, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Also equipped with LIGHTSYNC RGB powering flowing 8-LED lighting that’s customizable and adapts as you play with startup/power-down effects and battery optimization through active play detection. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor and more.
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    Top comment

    "The 502 is the best mouse hands down. All they did was make it wireless and better. ...Very comfortable if you have large hands, excellent battery life and very responsive."

    See all customer reviews

    Product Description

    G502 X PLUS, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Also equipped with LIGHTSYNC RGB powering flowing 8-LED lighting that’s customizable and adapts as you play with startup/power-down effects and battery optimization through active play detection. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor and more.
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    See all Gaming Mice
  8. ROCCAT - Kone XP Air Wireless Optical Gaming Mouse with Charging Dock and AIMO RGB Lighting - Black - Front_Zoom
    Top comment

    "My new favorite gaming mouse...I've used a pretty broad variety of gaming mice over the last few years and in general, every mouse has had at least one or two perks that I liked more than the others. ...I do not have a super large hand, but my thumb rests on 2 of the buttons and I cant turn them off. "

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    Product Description

    The ROCCAT Kone XP Air Wireless Ergonomic RGB Gaming Mouse is designed to put the functionality of actions and macros at your fingertips. Perfected through years of refinement, this mouse is equipped with 10 dedicated buttons plus left, right, and vertical scroll wheel click functionality to expand into 29 programmable inputs, thanks to the Easy-Shift[+] duplicator button. Want to take this mouse on the go? Switch between 2.4GHz Stellar Wireless and Bluetooth for the ultimate in versatility. Additionally, the Kone XP Air’s Charging Dock blends beautifully into your setup and comes equipped with a USB passthrough on the front for the 2.4GHz wireless adapter. To further the immersive RGB experience, the translucent shell and Krystal 4D Wheel set the stage for the Kone XP AIR’s 5 lighting zones, creating stunning lighting effects. ROCCAT AIMO lighting technology produces vibrant RGB lighting displays right out of the box or syncs with other compatible AIMO products. The Kone XP Air packs a performance punch with ROCCAT’s Optical Titan Switches for lightspeed actuation and Owl-Eye 19K dpi optical sensor for precise movements. The heat-treated glides and a Phantom Flex charging cable to even further amplify your unrestricted gameplay, giving you the fastest, smoothest, and most precise experience possible..
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    Top comment

    "My new favorite gaming mouse...I've used a pretty broad variety of gaming mice over the last few years and in general, every mouse has had at least one or two perks that I liked more than the others. ...I do not have a super large hand, but my thumb rests on 2 of the buttons and I cant turn them off. "

    See all customer reviews

    Product Description

    The ROCCAT Kone XP Air Wireless Ergonomic RGB Gaming Mouse is designed to put the functionality of actions and macros at your fingertips. Perfected through years of refinement, this mouse is equipped with 10 dedicated buttons plus left, right, and vertical scroll wheel click functionality to expand into 29 programmable inputs, thanks to the Easy-Shift[+] duplicator button. Want to take this mouse on the go? Switch between 2.4GHz Stellar Wireless and Bluetooth for the ultimate in versatility. Additionally, the Kone XP Air’s Charging Dock blends beautifully into your setup and comes equipped with a USB passthrough on the front for the 2.4GHz wireless adapter. To further the immersive RGB experience, the translucent shell and Krystal 4D Wheel set the stage for the Kone XP AIR’s 5 lighting zones, creating stunning lighting effects. ROCCAT AIMO lighting technology produces vibrant RGB lighting displays right out of the box or syncs with other compatible AIMO products. The Kone XP Air packs a performance punch with ROCCAT’s Optical Titan Switches for lightspeed actuation and Owl-Eye 19K dpi optical sensor for precise movements. The heat-treated glides and a Phantom Flex charging cable to even further amplify your unrestricted gameplay, giving you the fastest, smoothest, and most precise experience possible..
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    See all Gaming Mice
  9. Logitech - G705 Aurora Collection Wireless Optical Gaming Mouse with Customizable LIGHTSYNC RGB Lighting - White Mist - Front_Zoom
    Top comment

    "Perfect for my small hands - and it’s adorable!...Has helped relieve some of my hand/wrist discomfort during gaming from other bulkier and heavier mice I’ve used in the past. ...Great mouse for small hands....That does bring me to my favorite thing about the Logitech G705 Aurora mouse- its size. I have extremely small hands and most gaming mice are uncomfortable and cause fatigue during extended gaming sessions. "

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    Product Description

    The G705 Wireless Optical Gaming Mouse from The Aurora Collection is a compact wireless mouse designed to put the power of play in your hands with a contoured fit, soft RGB lighting, and gaming-grade tech. The sculpted design of the G705 makes the perfect companion for all-day, all-out play. This small wireless mouse is purpose-built for smaller hands and welcomes the palm, claw grip and fingertips of all kinds of players. Logitech Wireless Gaming Mouse lets you escape to anywhere, from everywhere, with a USB-C rechargeable, 40-hr battery life (while gaming with full lighting), LIGHTSPEED wireless, and Bluetooth connectivity.
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    Top comment

    "Perfect for my small hands - and it’s adorable!...Has helped relieve some of my hand/wrist discomfort during gaming from other bulkier and heavier mice I’ve used in the past. ...Great mouse for small hands....That does bring me to my favorite thing about the Logitech G705 Aurora mouse- its size. I have extremely small hands and most gaming mice are uncomfortable and cause fatigue during extended gaming sessions. "

    See all customer reviews

    Product Description

    The G705 Wireless Optical Gaming Mouse from The Aurora Collection is a compact wireless mouse designed to put the power of play in your hands with a contoured fit, soft RGB lighting, and gaming-grade tech. The sculpted design of the G705 makes the perfect companion for all-day, all-out play. This small wireless mouse is purpose-built for smaller hands and welcomes the palm, claw grip and fingertips of all kinds of players. Logitech Wireless Gaming Mouse lets you escape to anywhere, from everywhere, with a USB-C rechargeable, 40-hr battery life (while gaming with full lighting), LIGHTSPEED wireless, and Bluetooth connectivity.
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    See all Gaming Mice
  10. ROCCAT - Kone XP Wired Optical Gaming Ambidextrous Mouse with multi-button design & AIMO RGB lighting - Black - Front_Zoom
    Top comment

    "Great gamer mouse for scrolling....Scroll wheel works great and it fits comfortable in hand when gaming....Great mouse...Love it. Feels good in your hand. Lots of buttons for gaming."

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    Product Description

    The ROCCAT Kone XP 3D Lighting Gaming Mouse utilizes the refined ergonomics of the iconic Kone shape. The translucent shell sets the stage for the Kone XP’s 22 LEDs and 8 light guides, creating an unprecedented and immersive lighting experience. The Kone XP boasts 15 buttons, and thanks to ROCCAT’s Easy-Shift[+] duplicator technology there are 29 possible button functions. Ideal for gamers who demand deep customization. The Krystal 4D Wheel not only adds to the number of inputs, but also enhances the experience, beautifully diffusing the RGB lighting..
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    Top comment

    "Great gamer mouse for scrolling....Scroll wheel works great and it fits comfortable in hand when gaming....Great mouse...Love it. Feels good in your hand. Lots of buttons for gaming."

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    Product Description

    The ROCCAT Kone XP 3D Lighting Gaming Mouse utilizes the refined ergonomics of the iconic Kone shape. The translucent shell sets the stage for the Kone XP’s 22 LEDs and 8 light guides, creating an unprecedented and immersive lighting experience. The Kone XP boasts 15 buttons, and thanks to ROCCAT’s Easy-Shift[+] duplicator technology there are 29 possible button functions. Ideal for gamers who demand deep customization. The Krystal 4D Wheel not only adds to the number of inputs, but also enhances the experience, beautifully diffusing the RGB lighting..
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    See all Gaming Mice
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