A:AnswerYes, if it's equipped with Bluetooth. An optional USB Bluetooth receiver might also do the trick. But keep in mind that Macs this old are obsolete and will not run the latest OS, so you might consider a replacement.
A:AnswerEven if you get it to work, you should know that this kybd has a MAC SPECIFIC key layout. It will be confusing to use with a non-mac product. There are dozens of Bluetooth keyboards that will serve you better.