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Hello Rward, Thank you for reaching out to us. We appreciate your interest in Crucial products. We would like to inform you that the system Dell PowerEdge R640 supports 2.5 inch SATA SSDs: https://i.dell.com/sites/csdocuments/product_docs/en/poweredge-r640-spec-sheet.pdf The part Crucial - BX500 4TB Internal SSD SATA CT4000BX500SSD1 is compatible with your system. However, we do not recommend installing the consumer grade drives in Server, NAS, or Workstation. Crucial sells consumer grade SSDs which are designed for standard day to day use, like you would find in a personal desktop or laptop, other smaller mobile computing devices, and high-performance gaming/work systems. In an enterprise environment like a server, a drive can be subjected to 24/7 operation, often with a combination of high writes and erases. Enterprise drives like the Micron® 5400 or 7450, for example, are designed to handle continuous operation, with high amounts of erases and writes. A consumer drive will lose performance drastically when subjected to continuous writes, an enterprise drive will have a steady level of performance over the given period. This can also be said about the number of erases that an enterprise drive can handle compared to a consumer drive: https://www.crucial.com/support/articles-faq-ssd/installing-ssd-in-server-nas-workstation You can buy the Micron enterprise SSDs compatible with your server as given in the link : https://www.crucial.com/compatible-upgrade-for/dell/poweredge-r640 Thank you for your patience and understanding. Meanwhile, if you have any further query, please feel free to reach out to us. You can also visit our contact page: https://www.crucial.com/support/contact to know about other ways to reach out to us. Regards, Crucial
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