A:Answer If any audio amp has 2 RCA type connector jacks on the back panel labeled "CD" or "TAPE" or "VIDEO" or "VCR" or "AUX," then, yes, this player will hook right in with the red and black audio wires that come with it. Looks like the Bose unit uses a smaller-type AUX input, so, you will need to get an adapter cable. They cost around $5 and Best Buy should have them. Just tell them you need a stereo RCA to stereo 3.5mm "mini-jack" converter audio cable.