A:Answer This part is for older Chrysler, Dodge Jeep vehicles. The 2021 Durango would require one of our AmpPro pieces, the AP4-CH41(R.2) in order to add an amplifier to this vehicle. You do need to have the factory 7" or 8" radio for this to work. You can reach Tech Support at 727-592-5991 M-F 9am-8pm EST if you have more questions.