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Howdy Marquee, thank you for taking the time to ask us your question about the Samsung Galaxy Buds4 Pro. Yes, the Galaxy Buds4 Pro are compatible with the Galaxy S22+. They provide seamless, deep integration with Samsung devices running One UI, allowing features like easy pairing, 24-bit/96 kHz high-res audio, 360 audio with head tracking, auto-switching, and AI-powered voice controls via the wearable app. If you have any other questions for us, please feel free to reach out to Support. Thanks for being a valued Samsung customer. - Debra
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