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I don't see why it wouldn't. It should just replace your old card. You would obviously need to reinstall drivers but that's not hard to do. Hope this helps.
Sorry, there was a problem. Please try again later.It will probably work with an Acer of similar age and if you have the correct Pcie slot Available. Call Acer Sales and if they think they might sell an item they could tell you if it's compatible. The RX-580 was released about early 2017. I purchased mine in a Dell 5765 Desktop February 2017. You could also download the manual from Acer. This should list the open Pcie slots that are available. Good Luck! Hope it works out for you! Mike R.
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