A:AnswerNo.
You might be able to buy a specialty case, or turn this case upside down (with protection if there are vents on the top) but virtually all motherboards are designed in the same orientation, so it is unlikely.
A:AnswerRyan, thank you for your question about the board for this HP Omen gaming desktop! The HP Wolant board has a CPU TDP of 65 watts and uses an AM5 socket.
A:AnswerHi Ryan, thank you for asking. The HP OMEN 35L GT16-0364 uses the Wolant motherboard (SSID: 8CF4), which is compatible with specific AM5 processors. Currently, the Ryzen 7 8700G is the recommended upgrade for this model.
A:AnswerYes you can add a second Nve.M2 SSD using the second SSD slot under the GPU or you can use a traditional 2.5/3.5 hard drive. The case has a slot for either option.