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As long as your hp desktop is running windows 10 these will work perfectly. Just make sure to install the G hub software from the logitech website onto your desktop when the speakers arrive .
Sorry, there was a problem. Please try again later.Hello, yes these will work on a HP desktop PC. They have a few options to connect. You can connect them via Bluetooth, USB or 3.5 mm audio input. -Danielle from Logitech
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