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Yes, the Nikon D500 is compatible with AF-S type E lenses like the AF-S NIKKOR 200-500mm f/5.6E ED VR lens. Note that this lens is an FX-format lens, and the D500 is a DX-format camera body. Due to the 1.5x crop that occurs when an FX lens is mounted on a DX camera, the effective field of view would equal 300-750mm.
Sorry, there was a problem. Please try again later.YES, I use it with my Nikon D500 with great results. It is also compatible with Nikon Teleconvertors.
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