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Unfortunately, no. The HP Omen Obelisk is a micro-ATX case and the Asus ROG Strix B450-F is an ATX motherboard. The case is too small to fit the motherboard, unless you heavily modify the case.
Sorry, there was a problem. Please try again later.If you're asking if the CPU from the Obelisk 875 will work with this motherboard then I'm assuming that is an Intel CPU. Probably an I-5 right? Then the answer is no. The closest equivalent motherboard that would be compatible with an I-5 CPU would be the ASUS ROG strix H470-F gaming.
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