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You would have to remove the case if you wanted to use it.
Sorry, there was a problem. Please try again later.Yes, the iXpand drive can be used with OtterBox Defender case but it is a bit tricky. I've used it with the OtterBox Defender case on my iPhone SE. The hinged cover over the Lightning port that's part of the OtterBox case will fit up into the 180° bend of the iXpand drive but the 2 types of plastics don't slide along each other easily. I also purchased an iXpand 32GB Mini flash drive (WM $33); this is easier to connect since the 'Mini' drive doesn't have the return bend.
Sorry, there was a problem. Please try again later.I had difficulty fitting on my Otter Box case for my iPhone so I'd say it might on the iPad. However if you don't mind reversing it and having it overlap on your screen while you simply download onto it then it will fit fine.
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