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Not much...I own both...the 70-300 is heavier and is for full frame sensor...the 70-350 is for APS-C sensor is lighter and cheaper... so it depends on your camera and your needs...both are excellent for sports...wildlife etc...
Sorry, there was a problem. Please try again later.The 70-350 lens is made specifically for APS-C Cameras from sony (a6000, a6400, a6600 etc.). Where the 70-300 is made for Full Frame Cameras from Sony (a7iii, a7r iv, a9). Both can be used on APSC but using the 70-350 on a full frame will crop the image and essentially lower the resolution on a full frame camera.
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