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Best Buy customers often prefer the following products when searching for gaming mouse with side buttons.

A gaming mouse is one of the most important peripheral devices for your gaming setup. It's used to point to things on your screen, click on things, and move the pointer around the screen. The best mice are precise, comfortable to use, and have lots of buttons that can be programmed for different functions. Browse the top-ranked list of gaming mice with side buttons below along with associated reviews and opinions.

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  1. Razer - Naga V2 Pro MMO Wireless Optical Gaming Mouse with Interchangeable Side Plates in 2, 6, 12 Button Configurations - Black - Front_Zoom
    Top comment

    "The Naga V2 Pro is a really fun mouse for gaming. It provides many configurations, wireless and wired, 2, 6, or 12 button side configurations, and an app that allows for customizing lights, button modes, etc. the interchangeable plates on the side that allows for the 2, 6, and 12 button configurations have a solid magnetic connection and are super secure when in place. ...The mouse is smooth the buttons are smooth to press the interchangeable side buttons are nice, its a good mouse i recommend it...Amazing gaming mouse!"

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    Product Description

    Designed to dominate in MMO, battle royale, FPS, and more, the multi-genre master returns stronger than ever. With 3 swappable side plates, 19+1 programmable buttons, a Razer HyperScroll Pro Wheel, and Razer HyperSpeed Wireless, the Razer Naga V2 Pro packs the power to rise above every genre.
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    Top comment

    "The Naga V2 Pro is a really fun mouse for gaming. It provides many configurations, wireless and wired, 2, 6, or 12 button side configurations, and an app that allows for customizing lights, button modes, etc. the interchangeable plates on the side that allows for the 2, 6, and 12 button configurations have a solid magnetic connection and are super secure when in place. ...The mouse is smooth the buttons are smooth to press the interchangeable side buttons are nice, its a good mouse i recommend it...Amazing gaming mouse!"

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    Product Description

    Designed to dominate in MMO, battle royale, FPS, and more, the multi-genre master returns stronger than ever. With 3 swappable side plates, 19+1 programmable buttons, a Razer HyperScroll Pro Wheel, and Razer HyperSpeed Wireless, the Razer Naga V2 Pro packs the power to rise above every genre.
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    See all Gaming Mice
  2. Logitech - G502 X Wired Hyper-fast scroll Gaming Mouse with HERO 25K Sensor - White - Front_Zoom
    Top comment

    "Excellent mouse...Clean looking, comfortable and wire is flexible. I have the side thumb buttons set up as delete, enter and back for easy browsing. ...Awesome Mouse...Super fast, comfortable and lots of programmable buttons, everything you want in a gaming mouse."

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    Product Description

    G502 X, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. With HERO 25K sub-micron sensor, reversible and removable DPI-shift button, redesigned scroll wheel with dual hyper-fast and precise ratchet modes, thin-wall molding and lightweight design.
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    Top comment

    "Excellent mouse...Clean looking, comfortable and wire is flexible. I have the side thumb buttons set up as delete, enter and back for easy browsing. ...Awesome Mouse...Super fast, comfortable and lots of programmable buttons, everything you want in a gaming mouse."

    See all customer reviews

    Product Description

    G502 X, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. With HERO 25K sub-micron sensor, reversible and removable DPI-shift button, redesigned scroll wheel with dual hyper-fast and precise ratchet modes, thin-wall molding and lightweight design.
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    See all Gaming Mice
  3. Glorious - Model I Wired Optical 9 Buttons Honeycomb RGB Gaming Mouse - Matte Black - Front_Zoom
    Top comment

    "Feels very nice to use and the buttons on the side are nice to click...Mouse feels very professional. Great for a big hand and many uses with side buttons."

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    Product Description

    Our most feature-rich lightweight mouse yet. 9 Programmable buttons with 2 customizable magnetic thumb buttons put you in control. Looking at the highly-comfortable ergonomic shape, it's hard to believe the Model I is only 69g. Quickly adapt the Model I to your playstyle with its modular side buttons. Two of the four thumb buttons are easily-swappable for a perfect fit in your hand. Or you can use the flat shape option to completely remove their usability. Up to nine unique combinations are available for you to try out. The Model I becomes an extension of your arm for effortless control in all kinds of games. Its ergonomic body allows for a comfortable and confident grip that combats hand fatigue. Freely remap all the available buttons to your needs. Assign useful shortcuts, like instantly adjusting DPI by holding down a button, for custom control in games. Create and save up to three mouse profiles via Glorious CORE. Quickly switch between them to spend more time playing, less time tinkering.
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    Top comment

    "Feels very nice to use and the buttons on the side are nice to click...Mouse feels very professional. Great for a big hand and many uses with side buttons."

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    Product Description

    Our most feature-rich lightweight mouse yet. 9 Programmable buttons with 2 customizable magnetic thumb buttons put you in control. Looking at the highly-comfortable ergonomic shape, it's hard to believe the Model I is only 69g. Quickly adapt the Model I to your playstyle with its modular side buttons. Two of the four thumb buttons are easily-swappable for a perfect fit in your hand. Or you can use the flat shape option to completely remove their usability. Up to nine unique combinations are available for you to try out. The Model I becomes an extension of your arm for effortless control in all kinds of games. Its ergonomic body allows for a comfortable and confident grip that combats hand fatigue. Freely remap all the available buttons to your needs. Assign useful shortcuts, like instantly adjusting DPI by holding down a button, for custom control in games. Create and save up to three mouse profiles via Glorious CORE. Quickly switch between them to spend more time playing, less time tinkering.
    See all Gaming Mice
    See all Gaming Mice
  4. HyperX - Pulsefire Core Wired Optical Gaming Mouse with RGB Lighting - Pink - Front_Zoom
    Top comment

    "I love that it changes color, I programmed the buttons (which as been very handy). I don't like that I had to download an app for the mouse, but it feels good....Perfect mouse for gaming...Mine is pink which matches my setup great, but also has multiple buttons on the side for even more convenience when gaming."

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    Product Description

    The HyperX Pulsefire Core delivers the essentials for gamers looking for a solid, comfortable, wired RGB gaming mouse. The Pixart 3327 optical sensor gives players precise, smooth tracking with no hardware acceleration, and has native DPI settings up to 6200 DPI. The ergonomically-designed Pulsefire Core has textured side grips for a comfortable, no-slip grip, and its symmetrical shape is suitable for both palm and claw grip. It features high-quality switches with crisp tactile feedback rated for up to 20 million clicks. Customize lighting, DPI settings, and macros for 7 programmable buttons with HyperX NGENUITY software and set your mouse up just the way you want it. The large skates on Pulsefire Core help deliver accurate aiming by giving you a smooth, controlled glide as you move the mouse.
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    Top comment

    "I love that it changes color, I programmed the buttons (which as been very handy). I don't like that I had to download an app for the mouse, but it feels good....Perfect mouse for gaming...Mine is pink which matches my setup great, but also has multiple buttons on the side for even more convenience when gaming."

    See all customer reviews

    Product Description

    The HyperX Pulsefire Core delivers the essentials for gamers looking for a solid, comfortable, wired RGB gaming mouse. The Pixart 3327 optical sensor gives players precise, smooth tracking with no hardware acceleration, and has native DPI settings up to 6200 DPI. The ergonomically-designed Pulsefire Core has textured side grips for a comfortable, no-slip grip, and its symmetrical shape is suitable for both palm and claw grip. It features high-quality switches with crisp tactile feedback rated for up to 20 million clicks. Customize lighting, DPI settings, and macros for 7 programmable buttons with HyperX NGENUITY software and set your mouse up just the way you want it. The large skates on Pulsefire Core help deliver accurate aiming by giving you a smooth, controlled glide as you move the mouse.
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    See all Gaming Mice
  5. Razer - Orochi V2 Lightweight Wireless Optical Gaming Mouse With 950 Hour Battery Life - Quartz - Front_Zoom
    Top comment

    "Nice lightweight mouse. And its pink....Nice lightweight mouse. I was nervous at first because I felt the plastic felt a bit cheap but it was a gift and they love it and liked the feel compared to their old mouse that had rubberized grips on the side....Great lil Mouse...It is quick and works Great for her Gaming, and once again bonus for her its pink."

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    Product Description

    Introducing the Razer Orochi V2—a compact, ultra-lightweight wireless gaming mouse with the longest battery life in the market for peerless portable performance. Armed with an upgraded sensor and switches for crisp control, it’s the perfect partner for gaming on the go.
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    Top comment

    "Nice lightweight mouse. And its pink....Nice lightweight mouse. I was nervous at first because I felt the plastic felt a bit cheap but it was a gift and they love it and liked the feel compared to their old mouse that had rubberized grips on the side....Great lil Mouse...It is quick and works Great for her Gaming, and once again bonus for her its pink."

    See all customer reviews

    Product Description

    Introducing the Razer Orochi V2—a compact, ultra-lightweight wireless gaming mouse with the longest battery life in the market for peerless portable performance. Armed with an upgraded sensor and switches for crisp control, it’s the perfect partner for gaming on the go.
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    See all Gaming Mice
  6. Glorious - Model O Wireless Scroll Honeycomb RGB Gaming Mouse - Matte Black - Front_Zoom
    Top comment

    "Highly reocmmended lightweight mouse!...I did purchase this due to my launch day Model O wireless had an issue with the side buttons caving in but the replacement is perfect so far!...Great Mouse...Great mouse for gaming. 9/10. Would totally recommend,"

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    Product Description

    A high-performance, ultra-lightweight wireless mouse with proprietary BAMF sensor and No-lag wireless connectivity. BAMF is Glorious' newly developed pro-grade wireless sensor made in collaboration with Pixart. BAMF is optimized for high-performance, low-power draw. Specs include 400 IPS Tracking Speed, up to 19,000 programmable DPI, and up to 1000 Hz polling rate. No more shoddy stock mouse feet or buying 3rd party add-ons. Model O Wireless comes included with our premium G-Skates - 100% pure Virgin PTFE, rounded edges that don’t snag on your pad so your mouse will glide like blades on ice. Comes in 0.81mm thickness for maximum lifespan.
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    Top comment

    "Highly reocmmended lightweight mouse!...I did purchase this due to my launch day Model O wireless had an issue with the side buttons caving in but the replacement is perfect so far!...Great Mouse...Great mouse for gaming. 9/10. Would totally recommend,"

    See all customer reviews

    Product Description

    A high-performance, ultra-lightweight wireless mouse with proprietary BAMF sensor and No-lag wireless connectivity. BAMF is Glorious' newly developed pro-grade wireless sensor made in collaboration with Pixart. BAMF is optimized for high-performance, low-power draw. Specs include 400 IPS Tracking Speed, up to 19,000 programmable DPI, and up to 1000 Hz polling rate. No more shoddy stock mouse feet or buying 3rd party add-ons. Model O Wireless comes included with our premium G-Skates - 100% pure Virgin PTFE, rounded edges that don’t snag on your pad so your mouse will glide like blades on ice. Comes in 0.81mm thickness for maximum lifespan.
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    See all Gaming Mice
  7. Logitech - G502 X Wired USB Gaming Mouse with HERO 25K Sensor - Black - Front_Zoom
    Top comment

    "Logitech G502 X wired mouse...The only downside is it's a little heavy and the side buttons are easy to click accidentally when you don't need to. ...Tied for favorite mouse...However this one edges out on buttons and software. The four side buttons (or 5 if you change the snipe button) and software allows for extensive macros which puts it in functionality as the winner. "

    See all customer reviews

    Product Description

    G502 X, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. With HERO 25K sub-micron sensor, reversible and removable DPI-shift button, redesigned scroll wheel with dual hyper-fast and precise ratchet modes, thin-wall molding and lightweight design.
    See all Gaming Mice
    Top comment

    "Logitech G502 X wired mouse...The only downside is it's a little heavy and the side buttons are easy to click accidentally when you don't need to. ...Tied for favorite mouse...However this one edges out on buttons and software. The four side buttons (or 5 if you change the snipe button) and software allows for extensive macros which puts it in functionality as the winner. "

    See all customer reviews

    Product Description

    G502 X, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. With HERO 25K sub-micron sensor, reversible and removable DPI-shift button, redesigned scroll wheel with dual hyper-fast and precise ratchet modes, thin-wall molding and lightweight design.
    See all Gaming Mice
    See all Gaming Mice
  8. Glorious - Model D Wireless Optical Honeycomb RGB Gaming Mouse - Matte Black - Front_Zoom
    Top comment

    "Great mouse....Great mouse, very comfortable for big hands. Plenty of space for my thumb without accidentally clicking the 2 side buttons. ...Gaming mouse"

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    Product Description

    The Model D Wireless prevents double-clicking and unresponsiveness, producing an unbelievably smooth operation. The proprietary BAMF Sensor redefines what is possible in a gaming mouse. Made in collaboration with Pixart, BAMF is optimized for unrivaled performance with a lower power draw - allowing you to game harder and longer than ever before. The sensor provides pinpoint precision with its 400 IPS tracking speed, 19,000 programmable DPI, and up to 1000 Hz polling rate. At a mere 69 grams, the Model D Wireless is light weight and utilizes a right-handed, ergonomic design that satisfyingly cradles your palm. The Model D Wireless comes with a flexible USB-C Ascended charging cable for nonstop performance when you need it most. The mouse allows for seamless operation in wired and wireless modes. Its honeycomb shell helps reduce weight while maintaining strength.
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    Top comment

    "Great mouse....Great mouse, very comfortable for big hands. Plenty of space for my thumb without accidentally clicking the 2 side buttons. ...Gaming mouse"

    See all customer reviews

    Product Description

    The Model D Wireless prevents double-clicking and unresponsiveness, producing an unbelievably smooth operation. The proprietary BAMF Sensor redefines what is possible in a gaming mouse. Made in collaboration with Pixart, BAMF is optimized for unrivaled performance with a lower power draw - allowing you to game harder and longer than ever before. The sensor provides pinpoint precision with its 400 IPS tracking speed, 19,000 programmable DPI, and up to 1000 Hz polling rate. At a mere 69 grams, the Model D Wireless is light weight and utilizes a right-handed, ergonomic design that satisfyingly cradles your palm. The Model D Wireless comes with a flexible USB-C Ascended charging cable for nonstop performance when you need it most. The mouse allows for seamless operation in wired and wireless modes. Its honeycomb shell helps reduce weight while maintaining strength.
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    See all Gaming Mice
  9. Logitech - G502 X LIGHTSPEED Wireless Gaming Mouse with HERO 25K Sensor - Black - Front_Zoom
    Top comment

    "First Gaming Mice...Perfect for gaming and the extra buttons help with being a new mouse and keyboard player. ...My new favorite mouse!...Has all the buttons I need and I hit my shots even better than before."

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    Product Description

    G502 X LIGHTSPEED, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor, reversible and removable DPI-shift button, redesigned scroll wheel with dual hyper-fast and precise ratchet modes, thin-wall molding and lightweight design, optimized battery lasting for up to 140 gaming hours, and more.
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    Top comment

    "First Gaming Mice...Perfect for gaming and the extra buttons help with being a new mouse and keyboard player. ...My new favorite mouse!...Has all the buttons I need and I hit my shots even better than before."

    See all customer reviews

    Product Description

    G502 X LIGHTSPEED, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor, reversible and removable DPI-shift button, redesigned scroll wheel with dual hyper-fast and precise ratchet modes, thin-wall molding and lightweight design, optimized battery lasting for up to 140 gaming hours, and more.
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    See all Gaming Mice
  10. Glorious - Model O Minus Wireless Optical Honeycomb RGB Gaming Mouse - Matte Black - Front_Zoom
    Top comment

    "Has 4 customizable DPI speeds and 2 buttons on the side, charged immediately after opening and so far it has lasted 71+ hours....Excellent mouse...glorious always made appealing gaming mice, and this one looks and performs amazing!"

    See all customer reviews

    Product Description

    A high-performance, ultra-lightweight wireless mouse with proprietary BAMF sensor and No-lag wireless connectivity. BAMF is Glorious' newly developed pro-grade wireless sensor made in collaboration with Pixart. BAMF is optimized for high-performance, low-power draw. Specs include 400 IPS Tracking Speed, up to 19,000 programmable DPI, and up to 1000 Hz polling rate. No more shoddy stock mouse feet or buying 3rd party add-ons. Model O Wireless comes included with our premium G-Skates - 100% pure Virgin PTFE, rounded edges that don’t snag on your pad so your mouse will glide like blades on ice. Comes in 0.81mm thickness for maximum lifespan.
    See all Gaming Mice
    Top comment

    "Has 4 customizable DPI speeds and 2 buttons on the side, charged immediately after opening and so far it has lasted 71+ hours....Excellent mouse...glorious always made appealing gaming mice, and this one looks and performs amazing!"

    See all customer reviews

    Product Description

    A high-performance, ultra-lightweight wireless mouse with proprietary BAMF sensor and No-lag wireless connectivity. BAMF is Glorious' newly developed pro-grade wireless sensor made in collaboration with Pixart. BAMF is optimized for high-performance, low-power draw. Specs include 400 IPS Tracking Speed, up to 19,000 programmable DPI, and up to 1000 Hz polling rate. No more shoddy stock mouse feet or buying 3rd party add-ons. Model O Wireless comes included with our premium G-Skates - 100% pure Virgin PTFE, rounded edges that don’t snag on your pad so your mouse will glide like blades on ice. Comes in 0.81mm thickness for maximum lifespan.
    See all Gaming Mice
    See all Gaming Mice
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