Upgrade to smarter scrolling, better comfort, and more productivity with the Signature M650 L. The versatile mouse features an adaptive scroll SmartWheel that delivers line-by-line precision, and auto-switches to super-fast free spin mode with the flick of a finger. A choice of sizes for smaller, larger and left hands means there's a perfect fit for anyone. Seamless wireless connectivity, customizable side buttons, and a comfort shape keep you comfortably and productive hour after hour. Logitech’s SilentTouch technology delivers silent clicks to keep you focused – while the up to 24-month battery life and universal operating system compatibility ensure hassle-free performance.
A: Hey there Paul. The M650 has a ratcheted scroll wheel, so it should be tighter than that of the M325.
Q: How does the M650 differ from the M510(the best mouse ever made)?
A: The M650L builds on the M510's comfort with updated ergonomics, size options for a better fit, improved tracking, and optional silent clicks. It's essentially a modern upgrade.
A: You can hold it in either hand (I just tried it right now), and it doesn't feel awkward, although the side buttons will remain on the left side of the mouse, instead of where your thumb would be. Also, the Primary and Secondary mouse buttons (left and right click) would stay where they are, unless you use the Logitech software to remap and swap left and right click. TL;DR It doesn't feel awkward, but buttons and layout isn't specifically designed for left-handed people.
Q: Can the scroll wheel tilt for side scrolling?
A: No. But you can use the side button + scroll for side-scrolling
A: It’s definitely not necessary because I’ve been using it without one, but it’s also not a bad thing to have.
Q: Is this mouse USB-C compatible?
A: The Logitech Signature M650 connects wirelessly via Bluetooth Low Energy or with the included Logi Bolt USB receiver. It does not use USB-C. It connects via a standard USB-A port.
Q: Will this work on MacBook Pro?
A: Hey! Yes, the Signature M650 is compatible with macOS 10.10 or later.

Upgrade to smarter scrolling, better comfort, and more productivity with the Signature M650 L. The versatile mouse features an adaptive scroll SmartWheel that delivers line-by-line precision, and auto-switches to super-fast free spin mode with the flick of a finger. A choice of sizes for smaller, larger and left hands means there's a perfect fit for anyone. Seamless wireless connectivity, customizable side buttons, and a comfort shape keep you comfortably and productive hour after hour. Logitech’s SilentTouch technology delivers silent clicks to keep you focused – while the up to 24-month battery life and universal operating system compatibility ensure hassle-free performance.

Upgrade to smarter scrolling, better comfort, and more productivity with the Signature M550 – featuring SmartWheel scrolling that delivers precision and speed in an instant. A choice of sizes for smaller or larger hands means there's a perfect fit for anyone. Seamless wireless connectivity, silent clicks, and a comfort shape keep you comfortable and productive hour after hour.

The Design Collection Limited Edition mice mood-boosting designs bring a vibrant new look to your desk setup. Choose between different fun styles. It’s small, comfortable, super responsive, and completely wireless. Get total freedom with 10 m of wireless range, and work worry-free for 12 months on a single pre-installed battery. With smooth, line by line scrolling and precise cursor control for easier navigation at home or at work. The compact design perfectly fit users with smaller hands and kids—making it a great option for homeschooling.

Ready, set go! Move between screens and straight through your to-do list with Logitech M720 Triathlon, the athletic mouse built for endurance, versatility, and comfort. With EASY-SWITCH technology you can pair your mouse with up to 3 computers and seamlessly switch between them with a click of a button. Reliable hyper-fast scrolling lets you fly through documents and web pages or switch to click-to-click scrolling when you need precision. A true athlete, this portable mouse is designed to endure, with buttons built to withstand up to 10 million clicks. Focus on what really matters thanks to the extended battery life of up to 24 months of power on a single AA battery. Simply connect M720 Triathlon wirelessly via the included Logitech Unifying receiver or via Bluetooth smart technology. Download Logitech Options Software to unlock the full range of personalization for your Logitech mouse.
| Pros for Logitech - Signature M650 L Full-size Wireless Optical Scroll Mouse with Silent Clicks - Wireless - Blue | |||
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| Cons for Logitech - Signature M650 L Full-size Wireless Optical Scroll Mouse with Silent Clicks - Wireless - Blue | |||
Customers are enthusiastic about the Signature M650 L mouse, particularly its ease of use and comfortable size. Many appreciate the convenience of Bluetooth connectivity and the quietness of the silent clicks. While the side buttons are not silent, users are generally satisfied with the mouse's ergonomics, long battery life, and overall performance.
The vast majority of our reviews come from verified purchases. Reviews from customers may include My Best Buy members, employees, and Tech Insider Network members (as tagged). Select reviewers may receive discounted products, promotional considerations or entries into drawings for honest, helpful reviews.
After searching to replace my mouse that my dog chewed up, I settled on this one. I wanted the same model as I had before because it is red as well but couldn't find it in stock anywhere. I didn't look at the specs on this one too much, I just wanted a Logitech mouse and one that is big enough for my hand, I can't do dinky! I was surprised at how quiet this one was, it took some getting used to on not hearing the click. It glides well across my desk even without a mouse pad. I didn't realize until I got it home that it was Bluetooth so that's an added bonus for me since it frees up a USB port. The only thing I wish it included are instructions for the side buttons, yes I know I can look at it on Logitech's website for that but it would be helpful to have it in the box with the mouse. I also like that this came in an actual box and not plastic. I would recommend this mouse to anyone wanting a full size mouse!
This review is from Logitech - Signature M650 L Full-size Wireless Optical Scroll Mouse with Silent Clicks - Wireless - Red
Posted by Tammi
The Logitech Silent Mouse has been a great addition to my setup. The clicks are truly quiet, which makes it perfect for working late at night or in shared spaces without disturbing anyone. It’s very comfortable to hold, and the tracking is smooth on different surfaces. The battery life is impressive as well—I hardly ever need to replace it. Overall, it’s a reliable, lightweight, and surprisingly affordable mouse. If you want something quiet and easy to use, this is definitely a good choice.
This review is from Logitech - Signature M650 Wireless Optical Mouse with Silent Clicks - Wireless - Off-White
Posted by FengqingC
I recently purchased this Logitech full-size wireless optical scroll mouse, and I must say, it's been a fantastic addition to my setup! One of the standout features for me is the silent click functionality. As someone who often works in quiet environments, whether it be a library or a home office, the ability to click without making noise is a game-changer. The design of the mouse is sleek and ergonomic, making it comfortable for long hours of use. The optical scroll is smooth and responsive, allowing for effortless navigation through documents and web pages. The wireless feature also adds a level of convenience, as there are no tangled cords to worry about. Battery life has been impressive so far, lasting several weeks on a single charge, which is a significant plus in my book. Overall, if you're looking for a reliable and quiet mouse, this wireless optical scroll mouse is worth considering. It enhances productivity without disturbing those around you, truly merging functionality with a peaceful workspace!
This review is from Logitech - Signature M650 L Full-size Wireless Optical Scroll Mouse with Silent Clicks - Wireless - Graphite
Posted by TINAW