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Yes, the 50 series cards will work with a PC-Express 4.0 interface. There is no performance difference in testing between 5.0 and 4.0 for the 50 Series cards, there's barely a difference on a 3.0 interface. Benchmarks by TechPowerUp at 1080p/1440p/2160p for the 5090 provided.
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Sorry, there was a problem. Please try again later.The ASUS TUF-RTX5080-O16G-GAMING is compatible with a PCI Express 4.0 motherboard. However, it is designed to take full advantage of PCI Express 5.0, so pairing it with a PCIe 5.0 motherboard would unlock its maximum potential.
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