I've used the BOSE QC35's and am very happy.
I was also happy with the QC15 and QC25 when each came out. Each showed improved performance and sound isolation.
The only real advantage of the QC35 over the QC25 is that you may use a BT connection.
The 35's also have slightly better sound isolation, and a rechargeable battery.
The advantage of the 25's is that if you don't need wireless capacity, you also don't need to deal with charging your headphones...just drop in a single AAA battery for about 25 hours of continuous use. If you go that route, make sure you're only using premium lithium batteries, as they can give you upwards of 30 hours.'
Asthetically, the all black QC35's are a nice blend of comfort, sound quality and noise reduction. The microphone sounds great to people I call via cell phone, and the streaming box I use (ROKU) means that I can watch my movie without waking up the house. It also means that I can walk into the kitchen for a bottle of water without losing the sound of the movie. If my phone rings, I can take the call at the same time. While using my PC, I get great enjoyment out of being able to not hear the AC!