A:Answer Technically there was no MS Office version 2.0; for some reason they skipped and went from 1.x to 3.0 back in the early 90's. But to answer your question, since office, especially the early versions, were not hardware controlling...specifically addressing hard drive sectors or writing directly to a video controller, there should be no reason why not. A lot of products say they no longer support, in your case, Win 3.1, Win 95, Win 98, Win Me....and you must upgraded to support Win 10. True, they don't "support" it and probably never tested it, but it still works fine. I still run some older Win applications that were no longer supported past Win XP (and told I "must" upgrade) with no issues. Bottom line, I think it is time for you to upgrade unless there are specific feature that you've fell in love with, ie, like the old versions of Word Perfect (reveal codes)....ah memories....