A:Answer No, as the Venu Sq 2 does not have a microphone. You can answer the call on your watch, but would still need to talk through your phone.
To see what options are available for interacting with notifications and calls on a Garmin Watch, visit this link to the relevant Garmin Support Center article: https://support.garmin.com/en-US/?faq=Y7HkeoWBJp8xsQuLaE7sH8&productID=801643&searchQuery=answer&tab=topics