A:Answer 1. Pretty much any sytems can be modified, whcih would include the motherboard. However, that could be expensive.
2. If you are looking for fast secondary storage of 2TB to install is it necessary? I would ask yourself if the need is fast storage or do you have a greater need for larger storage like a USB or network external drive such as a 12 - 16 TB Western Digital Drive. These are availabel at Best Buy.
3. Ram -hyperx fury ddr4 ram and its 3200mhz ans I upgraded to 32 GB and it is fast.
Overall: Great case, easy to upgrade and performance is very good, add the ram and either game or work at home. It is up to the task.