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Thank you for your inquiry! The presence of isopropyl alcohol in the Insignia screen cleaner should generally be safe for use on smartphones with protective screens. Isopropyl alcohol is commonly used in screen cleaners because it evaporates quickly and is effective at removing dirt, oil, and fingerprints without leaving streaks. Keith | Insignia Support https://www.bestbuy.com/site/insignia-5-oz-screen-cleaning-solution-blue/8895009.p?skuId=8895009
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