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Hi Ruby, thank you for your interest in our Insignia - Replacement Remote for Samsung TVs. Definitely, this replacement remote will work on your Samsung Class M4500. For setting up this remote, it is easy to install. I also attached the user manual below, Go to page 1 and look for "Setting up your remote." In just 5 steps, you will be able to sync your remote. Ivy | Insignia Support https://files.bbystatic.com/rb%2F79TiQnC04lo8kda4ClQ%3D%3D/Quick%2Bsetup%2Bguide
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