A:AnswerI am not sure if the question os regarding the wire harness or the speakers that i purchased at the same time.
However, if its the speakers, im sure as long as you find out what size speakers are in that 2007 Toyota Hilander and get those sizes, they sure will work.
As far as the wire harness, you will have to ask Best buy so they can give you the one for your vehicle.
A:AnswerIt should work with those speakers without any issues. The harness has standard speaker connectors on one end and the other end has a matching female connector for a factory Toyota wiring harness with a male connector.