A:Answer Although these DSLR cameras are both very different from one another, each may have features that will appeal to you. One of the major differences between them is the sensor size; the Nikon D750 has a full frame (35.9mm x 24mm) CMOS sensor while the Nikon D500 has a DX (23.5mm x 15.7mm) CMOS sensor. Another difference is the megapixels that each offers; the Nikon D750 has an advantage with 24.3 megapixels, while the Nikon D500 has 20.9 megapixels. However, you may find that you enjoy the Nikon D500's touch-sensitive LCD, which can give you a 170° viewing angle, over the Nikon D750's wide-viewing angle TFT-LCD. Both have a duel card slot option; The D750 allowing you to have two SD memory cards and the D500 allowing you to have one XQD card and one SD memory card. Either one of these amazing DSLRs will make an exceptional addition to any growing DSLR bag. To learn more about the differences between these two remarkable camera models please contact Nikon Support.