A:Answer That is possible and its what I do, but remember these are "dumb" wired speakers, so your house must be wired to allow all the connections to your receiver/amp, and your receiver/amp has to have the ability to feed signals to different rooms in the manner you want. In my case I have three rooms, one receiver in each room, but the receivers are connected to each other with an optical splitter and cables in a way that allows me to play the same thing everywhere, or different sources (or nothing) in each room.