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I think yes. This drive is used internally and is a mechanical drive and is considered 3.5" HDD. I am not familiar with the Dell Optiplex 390, but I see that its specs can accept an internal drive that is 3.5".
Sorry, there was a problem. Please try again later.Hi Dante, Thank you for showing your interest in WD Blue internal drive. In order to check the compatibility, we would suggest you to please contact the motherboard or Laptop manufacturer. Need Help? Please see our "'Contact Us" page for information.
Sorry, there was a problem. Please try again later.Yes, it is compatible with a Dell Optiplex 390 Desktop.
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