A:AnswerBoth sides can be removed to install your gear. There are 2 thumb screws you will unscrew and then you can slide it to the back and left it away from the tower.
A:AnswerYes it can. I use an MB with the same dimensions and holding points. There is a black plastic stand off that can be screwed to the case to secure large motherboards. The msi z170-a pro atx lga1151 motherboard may not need it.