A:Answer Yes! I run this product through iCue. It will sense the pump head no matter what and you can have full control of the RGB then you have a decision to make with your two 120 fans on the radiator. You can have them controlled as part of the h100i, but I actually gave the h100i control of the fan power headers BUT I ran the aRGB for the fans into my lighting node pro and roll them up as part of my Commander Pro setup. This lets me sync my RGB a lot better since all 6 fans are addressed, in order, through the Commander Pro for lighting.
No harm either way, but this is what worked best for me.