Yes. The User's Guide does not list vellum specifically, but I just did a test print (color graphics with black text), using the "Plain paper" setting with Print quality "Normal," and it came out beautifully. I used 30 lb. Premium Translucent Vellum, which I had on hand. I love this printer! It got a workout its first few weeks with me: I printed a few hundred sheets, ranging from black-and-white to full color graphics with heavy ink coverage on various weights of paper, with excellent results every time.