A:AnswerIt's a little confusing but you need to use the buttons on the back of the monitor. The far right is power then there is a good gap. The first one after power is how you bring up the menu. the two middle ones after that move right to left. The far left will close the menu. Press the far right to select.
A:AnswerYes you can. I switch between my Xbox one and PC. I think its better than playing on a standard TV. This has gaming monitor response times. Which is 7ms which is unnoticeable.
A:AnswerYou would need a converter for the cables. This only have an HDMI and VGA cable. You would have to get a HDMI to thunderbolt if you have something like a newer iMac.
A:AnswerTechnically, monitors don't really have a strict compatibility to a certain OS. They're just plug-and-play.
What you should be worried about is the hardware on your computer and whether or not it has the performance to output the full resolution the display has to offer.