A:Answer At this point you've probably already made your choice, it being over 2 months since you asked, but on the bottom of the product box it has both the Windows 8 Compatible image and a Mac OS image and under System requirements it does list Max OS X (v10.6-10.8) in addition to Windows 8, 7, Vista and XP, also the the download page for the Razer Synapse software which you use to configure the mouse lists Windows 10 and Mac OS 10.8-10.10. I have been and currently use this mouse with Windows 10, so obviously these "requirements" on the box are not set in stone and you may be able to use it with other Windows and Mac OS versions, however there is currently no Synapse version available for Linux based OS's.