A:Answer Actually yes. I have MS and I can not play MMOs that do not allow mouse movements,..., only KEYBOARD MOVEMENT will keep me from playing. I have used mine on WoW, Rift, GW2, and NOW really loving this key pad on ESO. You can bind teh keys easily, you can use the toggle to make teh directional move that allow you to kite, backwards, you name it. Plenty of keys for ESO/GW2, but WoW LOVES it's multitude of attaches etc. Any direction, even "at angle you just go the main direction with your mouse and then add the toggle trick and you will become very good at kiting very quickly. It is really like playing the piano- I NEVER use my full size key board for movement OR attacks, all on my mouse and this well worth it Key Pad.- OAD