This product is a miniature, all-digital, strictly plug-and-play retro console.
It is about half the size of the original model one Sega Genesis, and I do not believe that original Sega Genesis carts would fit even if it did have a functioning cartridge drive, which I doubt that it does.
This is designed to be a 40 game nostalgic tribute/miniature replica of the Sega Genesis. It's main appeal and value is that the included selection of games outputs in HDMI to suit modern televisions, monitors, or displays, it includes 2 USB Sega Genesis controllers, it's small form factor, it's authentic retro/nostalgic branding, and that it is indeed going to be manufactured by Sega.
If you are searching for a modern solution for playing original Sega Genesis carts, I suggest the Analogue Mega SG.