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Best Buy customers often prefer the following products when searching for gaming mouse with keys.

A lot of gamers need more than just a mouse to perform well in their favorite games. They want to be able to use special abilities, change weapons, and open inventories with the press of a button. If you're one of those people, you'll want a gaming mouse with extra keys. Browse the top-ranked list of gaming mice with keys below along with associated reviews and opinions.

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  1. Glorious - Model O Wired Optical Honeycomb RGB Gaming Mouse - Matte Black - Front_Zoom
    Top comment

    "Good mouse for gaming lightweight i will recommended this to my friend...Gaming mouse for desktop work perfect highly recommend...Gaming mouse"

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    Product Description

    Model O’s Honeycomb Shell is the key to achieving a feather-light weight while maintaining its ultra-durable strength. You’ll barely feel the holes during gameplay, but they provide ventilation to keep your palms cool & fresh. Cleaning the Model O is easy, just use any air canister to keep your mouse good as new. Our braided cable is ultra-flexible and super lightweight, giving your mouse an almost wireless feel.
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    Top comment

    "Good mouse for gaming lightweight i will recommended this to my friend...Gaming mouse for desktop work perfect highly recommend...Gaming mouse"

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    Product Description

    Model O’s Honeycomb Shell is the key to achieving a feather-light weight while maintaining its ultra-durable strength. You’ll barely feel the holes during gameplay, but they provide ventilation to keep your palms cool & fresh. Cleaning the Model O is easy, just use any air canister to keep your mouse good as new. Our braided cable is ultra-flexible and super lightweight, giving your mouse an almost wireless feel.
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    Your price for this item is $49.99
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  2. Razer - DeathAdder V3 Pro Lightweight Wireless Optical Gaming Mouse with 90 Hour Battery - White - Front_Zoom
    Top comment

    "If youre a fan of ergonomic gaming mice this is worth a look!...Excellent Gaming Mouse!...Quick response time from the mouse while gaming. Would buy again."

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    Product Description

    With the Razer DeathAdder V3 Pro, victory takes on a new shape. Refined and reforged with the aid of top esports pros, its iconic ergonomic form is now more than 25% lighter than its predecessor, backed by a set of cutting-edge upgrades to push the limits of competitive play.
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    Top comment

    "If youre a fan of ergonomic gaming mice this is worth a look!...Excellent Gaming Mouse!...Quick response time from the mouse while gaming. Would buy again."

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    Product Description

    With the Razer DeathAdder V3 Pro, victory takes on a new shape. Refined and reforged with the aid of top esports pros, its iconic ergonomic form is now more than 25% lighter than its predecessor, backed by a set of cutting-edge upgrades to push the limits of competitive play.
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    Your price for this item is $149.99
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  3. SteelSeries - Aerox 5 Lightweight Wired Optical Gaming Mouse With 9 Programmble Buttons - Black - Front_Zoom
    Top comment

    "lightweight mouse...Due to the holes in the mouse, it's pretty lightweight and great to use whether it's for work or gaming. ...Great gaming mouse...Great mouse. Super responsive. Looks great on my desk and love it for gaming."

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    Product Description

    Empower yourself to command any battlefield with the ultra-lightweight, versatile Aerox 5. Victory is in your hand with a lightning-fast 66g build, featuring 9 programmable buttons for game-winning macros, a water-resistant AquaBarrier, flawless swiping with 100% PTFE glide skates, and ultra-precise, 1-to-1 tracking with the TrueMove Air sensor.
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    Top comment

    "lightweight mouse...Due to the holes in the mouse, it's pretty lightweight and great to use whether it's for work or gaming. ...Great gaming mouse...Great mouse. Super responsive. Looks great on my desk and love it for gaming."

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    Product Description

    Empower yourself to command any battlefield with the ultra-lightweight, versatile Aerox 5. Victory is in your hand with a lightning-fast 66g build, featuring 9 programmable buttons for game-winning macros, a water-resistant AquaBarrier, flawless swiping with 100% PTFE glide skates, and ultra-precise, 1-to-1 tracking with the TrueMove Air sensor.
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    Your price for this item is $63.99
    The previous price was $79.99
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  4. Logitech - G502 X PLUS LIGHTSPEED Wireless Gaming Mouse with HERO 25K Sensor - White - Front_Zoom
    Top comment

    "Best Mouse I have ever owned. Fits my hand nicely. I don't need a mouse pad. ...Amazing comfortable mouse...I have over 50 gaming mice and this one is amazine. Love how smooth and comfortable is feels. "

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    Product Description

    G502 X PLUS, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Also equipped with LIGHTSYNC RGB powering flowing 8-LED lighting that’s customizable and adapts as you play with startup/power-down effects and battery optimization through active play detection. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor and more.
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    Top comment

    "Best Mouse I have ever owned. Fits my hand nicely. I don't need a mouse pad. ...Amazing comfortable mouse...I have over 50 gaming mice and this one is amazine. Love how smooth and comfortable is feels. "

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    Product Description

    G502 X PLUS, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Also equipped with LIGHTSYNC RGB powering flowing 8-LED lighting that’s customizable and adapts as you play with startup/power-down effects and battery optimization through active play detection. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor and more.
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    Your price for this item is $159.99
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  5. Razer - Viper V2 Pro Lightweight Wireless Optical Gaming Mouse with 80 Hour Battery Life - Black - Front_Zoom
    Top comment

    "BEST MOUSE EVER !!!...This is easily the best mouse I have ever used. I love used a ton of gaming mice and this is the only one I will ever need....Razer Viper V2 Pro Wireless Gaming Mouse...Razer Viper V2 Pro Wireless Optical Gaming Mouse Black is an excellent gaming mouse."

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    Product Description

    Esports has a new apex predator. As successor to the award-winning Razer Viper Ultimate, our latest evolution is nearly 22% lighter and armed with all-round upgrades for enhanced performance. With one of the lightest wireless gaming mice ever, there’s now nothing holding you back.
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    Top comment

    "BEST MOUSE EVER !!!...This is easily the best mouse I have ever used. I love used a ton of gaming mice and this is the only one I will ever need....Razer Viper V2 Pro Wireless Gaming Mouse...Razer Viper V2 Pro Wireless Optical Gaming Mouse Black is an excellent gaming mouse."

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    Product Description

    Esports has a new apex predator. As successor to the award-winning Razer Viper Ultimate, our latest evolution is nearly 22% lighter and armed with all-round upgrades for enhanced performance. With one of the lightest wireless gaming mice ever, there’s now nothing holding you back.
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    Your price for this item is $149.99
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  6. ROCCAT - Kone XP Air Wireless Optical Gaming Mouse with Charging Dock and AIMO RGB Lighting - Black - Front_Zoom
    Top comment

    "My new favorite gaming mouse...I've used a pretty broad variety of gaming mice over the last few years and in general, every mouse has had at least one or two perks that I liked more than the others. ...An Excellent Gaming Mouse...The Roccat Kone XP-Air Wireless Ergonomic 3D Lighting Gaming Mouse is a beautiful thing! With a battery with a 100+ Hour Life before a quick charge on its docking station is required, this hard-wired or Bluetooth mouse is a keeper. "

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    Product Description

    The ROCCAT Kone XP Air Wireless Ergonomic RGB Gaming Mouse is designed to put the functionality of actions and macros at your fingertips. Perfected through years of refinement, this mouse is equipped with 10 dedicated buttons plus left, right, and vertical scroll wheel click functionality to expand into 29 programmable inputs, thanks to the Easy-Shift[+] duplicator button. Want to take this mouse on the go? Switch between 2.4GHz Stellar Wireless and Bluetooth for the ultimate in versatility. Additionally, the Kone XP Air’s Charging Dock blends beautifully into your setup and comes equipped with a USB passthrough on the front for the 2.4GHz wireless adapter. To further the immersive RGB experience, the translucent shell and Krystal 4D Wheel set the stage for the Kone XP AIR’s 5 lighting zones, creating stunning lighting effects. ROCCAT AIMO lighting technology produces vibrant RGB lighting displays right out of the box or syncs with other compatible AIMO products. The Kone XP Air packs a performance punch with ROCCAT’s Optical Titan Switches for lightspeed actuation and Owl-Eye 19K dpi optical sensor for precise movements. The heat-treated glides and a Phantom Flex charging cable to even further amplify your unrestricted gameplay, giving you the fastest, smoothest, and most precise experience possible..
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    Top comment

    "My new favorite gaming mouse...I've used a pretty broad variety of gaming mice over the last few years and in general, every mouse has had at least one or two perks that I liked more than the others. ...An Excellent Gaming Mouse...The Roccat Kone XP-Air Wireless Ergonomic 3D Lighting Gaming Mouse is a beautiful thing! With a battery with a 100+ Hour Life before a quick charge on its docking station is required, this hard-wired or Bluetooth mouse is a keeper. "

    See all customer reviews

    Product Description

    The ROCCAT Kone XP Air Wireless Ergonomic RGB Gaming Mouse is designed to put the functionality of actions and macros at your fingertips. Perfected through years of refinement, this mouse is equipped with 10 dedicated buttons plus left, right, and vertical scroll wheel click functionality to expand into 29 programmable inputs, thanks to the Easy-Shift[+] duplicator button. Want to take this mouse on the go? Switch between 2.4GHz Stellar Wireless and Bluetooth for the ultimate in versatility. Additionally, the Kone XP Air’s Charging Dock blends beautifully into your setup and comes equipped with a USB passthrough on the front for the 2.4GHz wireless adapter. To further the immersive RGB experience, the translucent shell and Krystal 4D Wheel set the stage for the Kone XP AIR’s 5 lighting zones, creating stunning lighting effects. ROCCAT AIMO lighting technology produces vibrant RGB lighting displays right out of the box or syncs with other compatible AIMO products. The Kone XP Air packs a performance punch with ROCCAT’s Optical Titan Switches for lightspeed actuation and Owl-Eye 19K dpi optical sensor for precise movements. The heat-treated glides and a Phantom Flex charging cable to even further amplify your unrestricted gameplay, giving you the fastest, smoothest, and most precise experience possible..
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    Your price for this item is $109.99
    The previous price was $129.99
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  7. Dell - Alienware Tri-Mode Wireless Gaming Ambidextrous Mouse - AW720M - Lunar Light - Lunar light - Front_Zoom
    Top comment

    "Overall great shape but a little too heavy for me after experiencing lightweight gaming mice...Great Gaming Mouse...This is a great ambidextrous gaming mouse. Whether you're righ or left handed, this mouse will feel comfortable and easy to use. "

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    Product Description

    Blaze through battlefields with a competition-ready wireless gaming mouse with 26,000 DPI, a slimmed-down design and magnetic-snap fast-charging.
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    Top comment

    "Overall great shape but a little too heavy for me after experiencing lightweight gaming mice...Great Gaming Mouse...This is a great ambidextrous gaming mouse. Whether you're righ or left handed, this mouse will feel comfortable and easy to use. "

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    Product Description

    Blaze through battlefields with a competition-ready wireless gaming mouse with 26,000 DPI, a slimmed-down design and magnetic-snap fast-charging.
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    Your price for this item is $149.99
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  8. Logitech - G705 Aurora Collection Wireless Optical Gaming Mouse with Customizable LIGHTSYNC RGB Lighting - White Mist - Front_Zoom
    Top comment

    "Nice mouse, a little pricey...It is a great mouse that fits my very small hands. My only complaint (and it's a small one) is that it is a fair bit heavier than other larger gaming mice. ...A pretty good mouse...Probably the most comfortable mouse I've owned. It fits perfectly in my hand and the side keys are placed so they're easy to press. "

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    Product Description

    The G705 Wireless Optical Gaming Mouse from The Aurora Collection is a compact wireless mouse designed to put the power of play in your hands with a contoured fit, soft RGB lighting, and gaming-grade tech. The sculpted design of the G705 makes the perfect companion for all-day, all-out play. This small wireless mouse is purpose-built for smaller hands and welcomes the palm, claw grip and fingertips of all kinds of players. Logitech Wireless Gaming Mouse lets you escape to anywhere, from everywhere, with a USB-C rechargeable, 40-hr battery life (while gaming with full lighting), LIGHTSPEED wireless, and Bluetooth connectivity.
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    Top comment

    "Nice mouse, a little pricey...It is a great mouse that fits my very small hands. My only complaint (and it's a small one) is that it is a fair bit heavier than other larger gaming mice. ...A pretty good mouse...Probably the most comfortable mouse I've owned. It fits perfectly in my hand and the side keys are placed so they're easy to press. "

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    Product Description

    The G705 Wireless Optical Gaming Mouse from The Aurora Collection is a compact wireless mouse designed to put the power of play in your hands with a contoured fit, soft RGB lighting, and gaming-grade tech. The sculpted design of the G705 makes the perfect companion for all-day, all-out play. This small wireless mouse is purpose-built for smaller hands and welcomes the palm, claw grip and fingertips of all kinds of players. Logitech Wireless Gaming Mouse lets you escape to anywhere, from everywhere, with a USB-C rechargeable, 40-hr battery life (while gaming with full lighting), LIGHTSPEED wireless, and Bluetooth connectivity.
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    Your price for this item is $79.99
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  9. Razer - Viper V2 Pro Lightweight Wireless Optical Gaming Mouse with 80 Hour Battery Life - White - Front_Zoom
    Top comment

    "Great wireless gaming mouse...Did the job but it wasn't a gaming mouse. I have tried Logitech gaming mice before and other various Razer ones as well. ...Mouse?? What Mouse?...The Razer - Viper V2 Pro Wireless Optical Gaming Mouse (Officially I do believe) the lightest gaming mouse out there. "

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    Product Description

    Esports has a new apex predator. As successor to the award-winning Razer Viper Ultimate, our latest evolution is nearly 22% lighter and armed with all-round upgrades for enhanced performance. With one of the lightest wireless gaming mice ever, there’s now nothing holding you back.
    See all Gaming Mice
    Top comment

    "Great wireless gaming mouse...Did the job but it wasn't a gaming mouse. I have tried Logitech gaming mice before and other various Razer ones as well. ...Mouse?? What Mouse?...The Razer - Viper V2 Pro Wireless Optical Gaming Mouse (Officially I do believe) the lightest gaming mouse out there. "

    See all customer reviews

    Product Description

    Esports has a new apex predator. As successor to the award-winning Razer Viper Ultimate, our latest evolution is nearly 22% lighter and armed with all-round upgrades for enhanced performance. With one of the lightest wireless gaming mice ever, there’s now nothing holding you back.
    See all Gaming Mice
    Your price for this item is $149.99
    See all Gaming Mice
  10. ROCCAT - Kone XP Wired Optical Gaming Ambidextrous Mouse with multi-button design & AIMO RGB lighting - Black - Front_Zoom
    Top comment

    "Binding key problem...It’s a good mouse except this one was giving me trouble when I was assigning my keys to the extra buttons. ...Thought i would try out one of their mice when my old one stopped working properly. "

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    Product Description

    The ROCCAT Kone XP 3D Lighting Gaming Mouse utilizes the refined ergonomics of the iconic Kone shape. The translucent shell sets the stage for the Kone XP’s 22 LEDs and 8 light guides, creating an unprecedented and immersive lighting experience. The Kone XP boasts 15 buttons, and thanks to ROCCAT’s Easy-Shift[+] duplicator technology there are 29 possible button functions. Ideal for gamers who demand deep customization. The Krystal 4D Wheel not only adds to the number of inputs, but also enhances the experience, beautifully diffusing the RGB lighting..
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    Top comment

    "Binding key problem...It’s a good mouse except this one was giving me trouble when I was assigning my keys to the extra buttons. ...Thought i would try out one of their mice when my old one stopped working properly. "

    See all customer reviews

    Product Description

    The ROCCAT Kone XP 3D Lighting Gaming Mouse utilizes the refined ergonomics of the iconic Kone shape. The translucent shell sets the stage for the Kone XP’s 22 LEDs and 8 light guides, creating an unprecedented and immersive lighting experience. The Kone XP boasts 15 buttons, and thanks to ROCCAT’s Easy-Shift[+] duplicator technology there are 29 possible button functions. Ideal for gamers who demand deep customization. The Krystal 4D Wheel not only adds to the number of inputs, but also enhances the experience, beautifully diffusing the RGB lighting..
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    Your price for this item is $59.99
    The previous price was $69.99
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