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Left Handed Optical Mouse

A mouse is one of the most important peripherals for your computer, and there are a lot of different options out there. If you're left-handed, it can be hard to find a mouse that feels natural and works well for you. Fortunately, we have just the products that can help you. Browse the top-ranked list of left-handed optical mice below along with associated reviews and opinions.

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  1. Logitech - M310 Wireless Optical Ambidextrous Mouse - Wireless - Silver

    SKU: J7H7ZLV3V9

    Product Description

    A wireless silver mouse with ambidextrous ergonomic design, soft rubber grips, and smooth, responsive tracking.
    See all Mice
    Your price for this item is $18.99
    Save $4
    The previous price was $22.99

  2. Logitech - Signature M650 Wireless Optical Mouse with Silent Clicks - Wireless - Rose

    SKU: J7H7ZY3W3K

    Product Description

    A wireless rose mouse with silent clicks, SmartWheel scrolling, customizable buttons, and long battery life.
    See all Mice
    Your price for this item is $29.99
    Save $10
    The previous price was $39.99

  3. Logitech - Lift Vertical Wireless Optical Ergonomic Mouse with 4 Customizable Buttons - Wireless - Graphite

    SKU: J7H7ZY3F9C

    Product Description

    An ergonomic graphite wireless mouse with quiet clicks, 4 customizable buttons, and a comfortable vertical design.
    See all Mice
    Your price for this item is $69.99
    Save $10
    The previous price was $79.99

  4. Logitech - M196 Lightweight Bluetooth Wireless Optical Mouse Compact 3-Button Ambidextrous Mouse with Smooth Tracking - Wireless - Graphite

    SKU: J7H7ZYG47F

    The clicking of the buttons is loud compared to modern higher-priced mice, but it isn't louder than the original mice that were available in the 1980s. ...This mouse feels more ergonomic in my hand than...

    Product Description

    A compact graphite wireless mouse featuring Bluetooth connectivity, ambidextrous design, and smooth optical tracking.
    See all Mice
    Your price for this item is $11.99
    Save $1
    The previous price was $12.99

  5. Logitech - Lift for Business Vertical Ergonomic Left Handed Wireless Mouse - Wireless - Graphite

    SKU: J7H7ZY3FP3

    Product Description

    An ergonomic left-handed wireless mouse in graphite, designed for comfort, security, and all-day productivity.
    See all Wireless & Bluetooth Mice
    Your price for this item is $69.99
    Save $10
    The previous price was $79.99

  6. Logitech - M310 Wireless Optical Ambidextrous Mouse - Wireless - Flame Red

    SKU: J7H7ZLV5SQ

    Product Description

    A wireless, ambidextrous mouse in flame red with ergonomic design, soft rubber grips, and smooth tracking.
    See all Mice
    Your price for this item is $18.99
    Save $4
    The previous price was $22.99

  7. Microsoft - Surface Bluetooth Optical Ambidextrous Mouse - Wireless - Silver

    SKU: J3ZKKZKRFQ

    MICROSOFT SURVACE WIRELEE OPTICAL MOUSE...This mouse works great, easy to operate, and no problems...Works great with my new windows laptop! I am left handed but have gotten used to right hand mouse,...

    Product Description

    A wireless silver mouse with Bluetooth connectivity, ambidextrous design, and a comfortable metal scroll wheel.
    See all Mice
    Your price for this item is $59.99

  8. Logitech - Lift for Mac Wireless Bluetooth Optical Ergonomic Mouse with 4 Customizable Buttons - Wireless - Off-White

    SKU: J7H7ZY3FQH

    Product Description

    An ergonomic off-white Bluetooth mouse with quiet clicks, four customizable buttons, and a vertical design for comfort.
    See all Mice
    Your price for this item is $81.99

  9. CORSAIR - M75 WIRELESS Lightweight Optical RGB Gaming Ambidextrous Mouse - Wireless - White

    SKU: J39QHT7RGR

    Best mouse I’ve ever had...I started out with a Logitech mouse and kept having issues with it went back to Best Buy and one of the representatives recommended this mouse have to say probably the best...

    Product Description

    An ambidextrous white wireless gaming mouse with 26,000 DPI optical sensor and customizable RGB lighting.
    See all Gaming Mice
    Your price for this item is $59.99
    Save $70
    The previous price was $129.99

  10. CORSAIR - M75 WIRELESS Lightweight Optical RGB Gaming Ambidextrous Mouse - Wireless - Black

    SKU: J39QHTJZ97

    Product Description

    An ultra-lightweight black wireless gaming mouse with 26K DPI optical sensor and customizable RGB lighting.
    See all Gaming Mice
    Your price for this item is $49.99
    Save $80
    The previous price was $129.99
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In-store pricing may vary. Prices and offers are subject to change. © 2026 Best Buy. All rights reserved. BEST BUY, the BEST BUY logo, the tag design, and MY BEST BUY are trademarks of Best Buy and its affiliated companies.