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Best Buy customers often prefer the following products when searching for left-handed wireless mouse.

If you're left-handed, finding a mouse that feels natural can be tricky. Most mice are designed for righties, but there are some left-handed mice that offer comfort and control for your left hand. Browse the top-ranked list of left-handed wireless mice below along with associated reviews and opinions.

Main Results
  1. Logitech - Lift Left Vertical Wireless Ergonomic Left-Handed Mouse with 4 Customizable Buttons - Graphite - Front_Zoom
    Top comment

    "Like the ergonomics and left handed, 2. No instructions showing where left and right click buttons are. ...I previously used the Logitech M650 Left Handed Mouse which I really, really loved. ...Best left handed mouse!...Lefty Mouse"

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    Product Description

    Desk life getting you down? Lift yourself up with Lift Vertical Ergonomic Mouse – a comfy and intuitive wireless mouse with quiet clicks crafted specially for small-to-medium hands. Available in right and left. Lift’s unique 57-degree angle elevates your wrist to give a feeling of relief — and sends a wave of comfort through the forearm and upper body. Scrolling feels second nature with SmartWheel, which easily shifts from precision to speed-scroll. Customize Lift ergo mouse using intuitive Logi Options+ Software.
    See all Wireless & Bluetooth Mice
    Top comment

    "Like the ergonomics and left handed, 2. No instructions showing where left and right click buttons are. ...I previously used the Logitech M650 Left Handed Mouse which I really, really loved. ...Best left handed mouse!...Lefty Mouse"

    See all customer reviews

    Product Description

    Desk life getting you down? Lift yourself up with Lift Vertical Ergonomic Mouse – a comfy and intuitive wireless mouse with quiet clicks crafted specially for small-to-medium hands. Available in right and left. Lift’s unique 57-degree angle elevates your wrist to give a feeling of relief — and sends a wave of comfort through the forearm and upper body. Scrolling feels second nature with SmartWheel, which easily shifts from precision to speed-scroll. Customize Lift ergo mouse using intuitive Logi Options+ Software.
    See all Wireless & Bluetooth Mice
    See all Wireless & Bluetooth Mice
  2. Samsung - Silicone Grip Cover for Galaxy Z Fold4 - Black - Front_Zoom
    Top comment

    "Love the hand safety strap for easy one handed grip. Only problem is that it limits the wireless charging unless you remove the back portion case...It just felt right and the strap is okay. For those who is a lefty or a righty itll be a little complicated. The phone is a bit heavy, once you use the strap itll feel a little uncomfortable but overall i love the case."

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    Product Description

    The Galaxy Z Fold4 Silicone Grip Cover has silicone built to endure your everyday life, and the silicone strap on the back secures your grip on your phone – helping to keep it safely in your hand and not on the floor.
    See all Cell Phone Cases
    Top comment

    "Love the hand safety strap for easy one handed grip. Only problem is that it limits the wireless charging unless you remove the back portion case...It just felt right and the strap is okay. For those who is a lefty or a righty itll be a little complicated. The phone is a bit heavy, once you use the strap itll feel a little uncomfortable but overall i love the case."

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    Product Description

    The Galaxy Z Fold4 Silicone Grip Cover has silicone built to endure your everyday life, and the silicone strap on the back secures your grip on your phone – helping to keep it safely in your hand and not on the floor.
    See all Cell Phone Cases
    See all Cell Phone Cases
  3. Bella Pro Series - 8-Cup Pour Over Coffee Maker - Stainless Steel - Front_Zoom
    Top comment

    "Adds a little extra morning mental stimulation to pour the coffee left handed, I've made a little game out of it. "

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    Product Description

    Consistently rich and piping hot—the two things that matter most when it comes to coffee. Expect that and more with the Bella Pro Series 8-Cup Pour Over Coffee Maker featuring a flavor-infusion carafe lid, easy-fill water tank, stain-resistant heating plate, and stainless steel design.
    See all Pour-Over Coffee Makers
    Top comment

    "Adds a little extra morning mental stimulation to pour the coffee left handed, I've made a little game out of it. "

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    Product Description

    Consistently rich and piping hot—the two things that matter most when it comes to coffee. Expect that and more with the Bella Pro Series 8-Cup Pour Over Coffee Maker featuring a flavor-infusion carafe lid, easy-fill water tank, stain-resistant heating plate, and stainless steel design.
    See all Pour-Over Coffee Makers
    See all Pour-Over Coffee Makers
  4. Shark Rotator with PowerFins HairPro and Odor Neutralizer Technology Upright Vacuum - Charcoal - Front_Zoom
    Top comment

    "My husband finds it a bit tricky to use as a lefty due to cord placement and where you put your foot to release the handle for use. ...Left a strong clean smell on my furniture after"

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    Product Description

    The Shark Rotator Pet Upright Vacuum with PowerFins HairPro Brushroll pulls embedded pet hair from carpets and floors. Odor Neutralizer Technology guards against bad odors inside your vacuum for a fresh-smelling home, while the self-cleaning brushroll delivers powerful pet hair pickup without hair wrap. Includes a 3XL-capacity dust cup, and Anti-Allergen Complete Seal with HEPA filtration.
    See all Upright Vacuums
    Top comment

    "My husband finds it a bit tricky to use as a lefty due to cord placement and where you put your foot to release the handle for use. ...Left a strong clean smell on my furniture after"

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    Product Description

    The Shark Rotator Pet Upright Vacuum with PowerFins HairPro Brushroll pulls embedded pet hair from carpets and floors. Odor Neutralizer Technology guards against bad odors inside your vacuum for a fresh-smelling home, while the self-cleaning brushroll delivers powerful pet hair pickup without hair wrap. Includes a 3XL-capacity dust cup, and Anti-Allergen Complete Seal with HEPA filtration.
    See all Upright Vacuums
    See all Upright Vacuums
  5. Turtle Beach - VelocityOne Flightstick Universal Simulation Controller for Xbox Series X and Windows PCs - Front_Zoom
    Top comment

    "The action’s a little stiff on center as new, but with the hall effect sensors it should have good longevity, and importantly for me, a lefty, it’s ambidextrous....The stick features a soft rubberized grip and an adjustable wrist support that you can swap between five different heights as well as converting it to left handed. It has two throttles with swappable texturized rubber handles. "

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    Product Description

    The Turtle Beach VelocityOne Flightstick for Xbox Series X|S, Xbox One & Windows 10 & 11 PCs equips you with immersive, accurate controls for navigating air and space flight simulation & combat games on Xbox and PC. High resolution non-contact sensors provide precise response and extended longevity to the main stick controls, while throttle and flap levers control main engine power and make for quick adjustment of secondary control surfaces. Plus, the levers can be customized with swappable throttle heads to suit the aircraft you are flying. Precision detents at the minimum and maximum positions allow activation of full reverse thrust at minimum, and afterburner, boost or Take Off/Go Around thrust at maximum. An ultra-precise nano trim wheel allows for fine tuning of attitude, and an analog POV hat allows freelook in cockpit views or strafe thrusters in space simulation games. An OLED Flight Management Display makes for easy adjustments to control profiles, trim wheel input mode, rudder lock and more. Navigate the FMD using an intuitive rotary dial with click at the base of the stick to configure, and update product performance in real-time with all information stored in on-board memory. 27 programmable buttons, stick mounted buttons, dual throttle lever detents and 8 programmable base buttons equip you with an arsenal of adjustable controls to your most critical simulation functions. Pilot fighter jets or airliners thanks to an ambidextrous right and left-handed design with a reversible wrist rest, and programmable base buttons allow the entire setup to be configured for right, or left-handed controls. Take customization a step further and adjust the color, brightness and response of multiple RGB LED zones. Familiar Xbox controls allow for easy console operation, and you can switch input mode to PC to play across a wide range of simulation titles.
    See all Joysticks
    Top comment

    "The action’s a little stiff on center as new, but with the hall effect sensors it should have good longevity, and importantly for me, a lefty, it’s ambidextrous....The stick features a soft rubberized grip and an adjustable wrist support that you can swap between five different heights as well as converting it to left handed. It has two throttles with swappable texturized rubber handles. "

    See all customer reviews

    Product Description

    The Turtle Beach VelocityOne Flightstick for Xbox Series X|S, Xbox One & Windows 10 & 11 PCs equips you with immersive, accurate controls for navigating air and space flight simulation & combat games on Xbox and PC. High resolution non-contact sensors provide precise response and extended longevity to the main stick controls, while throttle and flap levers control main engine power and make for quick adjustment of secondary control surfaces. Plus, the levers can be customized with swappable throttle heads to suit the aircraft you are flying. Precision detents at the minimum and maximum positions allow activation of full reverse thrust at minimum, and afterburner, boost or Take Off/Go Around thrust at maximum. An ultra-precise nano trim wheel allows for fine tuning of attitude, and an analog POV hat allows freelook in cockpit views or strafe thrusters in space simulation games. An OLED Flight Management Display makes for easy adjustments to control profiles, trim wheel input mode, rudder lock and more. Navigate the FMD using an intuitive rotary dial with click at the base of the stick to configure, and update product performance in real-time with all information stored in on-board memory. 27 programmable buttons, stick mounted buttons, dual throttle lever detents and 8 programmable base buttons equip you with an arsenal of adjustable controls to your most critical simulation functions. Pilot fighter jets or airliners thanks to an ambidextrous right and left-handed design with a reversible wrist rest, and programmable base buttons allow the entire setup to be configured for right, or left-handed controls. Take customization a step further and adjust the color, brightness and response of multiple RGB LED zones. Familiar Xbox controls allow for easy console operation, and you can switch input mode to PC to play across a wide range of simulation titles.
    See all Joysticks
    See all Joysticks
  6. Logitech - MX Anywhere 3S Wireless Bluetooth Fast Scrolling Mouse with Programmable Buttons - Black - Front_Zoom
    Top comment

    "Great bag friendly version of Logitech's mice...The MX Anywhere is a great option for that. This mouse has what feels like a semi ergonomic design, that could also be used right or left handed. ...The gold standard for a PC mouse...Still a great mouse for desktop use however, personally, I think larger mice work better there."

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    Product Description

    Introducing Logitech MX Anywhere 3S Mouse, a beloved compact wireless mouse with next-level precision and control – now with 8K DPI Any-Surface Tracking and Quiet Clicks so you can master your work anywhere.
    See all Wireless & Bluetooth Mice
    Top comment

    "Great bag friendly version of Logitech's mice...The MX Anywhere is a great option for that. This mouse has what feels like a semi ergonomic design, that could also be used right or left handed. ...The gold standard for a PC mouse...Still a great mouse for desktop use however, personally, I think larger mice work better there."

    See all customer reviews

    Product Description

    Introducing Logitech MX Anywhere 3S Mouse, a beloved compact wireless mouse with next-level precision and control – now with 8K DPI Any-Surface Tracking and Quiet Clicks so you can master your work anywhere.
    See all Wireless & Bluetooth Mice
    See all Wireless & Bluetooth Mice
  7. Razer DeathAdder V3 Ultra-lightweight Ergonomic Esports Mouse - Black - Front_Zoom
    Top comment

    "Great mouse especially for gaming....What I like to do is set the mouse left click to the other thumb button (I like to use one of the thumb buttons as the hypershift key) or set the left mouse button to be the bottom dpi button if you would like to asign the left mouse button to something else. ...This is a great simple ergonomic mouse for right handed people. It has no flashing lights, its pretty light for quick movements and its really responsive."

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    Product Description

    With the Razer DeathAdder V3, victory takes on a new shape. Refined and reforged with the aid of top esports pros, its iconic ergonomic form is now more than 25% lighter than its predecessor, backed by a set of cutting-edge upgrades to push the limits of competitive play.
    See all Gaming Mice
    Top comment

    "Great mouse especially for gaming....What I like to do is set the mouse left click to the other thumb button (I like to use one of the thumb buttons as the hypershift key) or set the left mouse button to be the bottom dpi button if you would like to asign the left mouse button to something else. ...This is a great simple ergonomic mouse for right handed people. It has no flashing lights, its pretty light for quick movements and its really responsive."

    See all customer reviews

    Product Description

    With the Razer DeathAdder V3, victory takes on a new shape. Refined and reforged with the aid of top esports pros, its iconic ergonomic form is now more than 25% lighter than its predecessor, backed by a set of cutting-edge upgrades to push the limits of competitive play.
    See all Gaming Mice
    See all Gaming Mice
  8. Logitech - Lift for Mac Bluetooth Ergonomic Mouse with 4 Customizable Buttons - Off-White - Front_Zoom
    Top comment

    "Good for office use, not for gaming nor lefty....I bought this mouse because of pain in my right palm after a long day working. ...An ergonomic mouse good for M1 + Newer Macs...This mouse is designed for small to medium hands and comes in right-handed and left-handed models."

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    Product Description

    Designed for Mac, made for comfort. Logitech Lift ergonomic vertical mouse for Mac is a comfy and intuitive Bluetooth wireless mouse with quiet clicks crafted specially for small to medium hands. This wireless small mouse's unique 57-degree angle elevates your wrist to give a feeling of relief — and sends a wave of comfort through the forearm and upper body. Scrolling on this quiet mouse feels like second nature with the silent SmartWheel, which seamlessly shifts from precision to speed-scroll. Customise your Logitech ergo mouse using intuitive Logi Options+ Software. Easily assign each of the quiet click mouse’s 4 easy-to-reach customisable buttons to a handy shortcut – and program them to change as you hop between apps.
    See all Wireless & Bluetooth Mice
    Top comment

    "Good for office use, not for gaming nor lefty....I bought this mouse because of pain in my right palm after a long day working. ...An ergonomic mouse good for M1 + Newer Macs...This mouse is designed for small to medium hands and comes in right-handed and left-handed models."

    See all customer reviews

    Product Description

    Designed for Mac, made for comfort. Logitech Lift ergonomic vertical mouse for Mac is a comfy and intuitive Bluetooth wireless mouse with quiet clicks crafted specially for small to medium hands. This wireless small mouse's unique 57-degree angle elevates your wrist to give a feeling of relief — and sends a wave of comfort through the forearm and upper body. Scrolling on this quiet mouse feels like second nature with the silent SmartWheel, which seamlessly shifts from precision to speed-scroll. Customise your Logitech ergo mouse using intuitive Logi Options+ Software. Easily assign each of the quiet click mouse’s 4 easy-to-reach customisable buttons to a handy shortcut – and program them to change as you hop between apps.
    See all Wireless & Bluetooth Mice
    See all Wireless & Bluetooth Mice
  9. Logitech - G502 X PLUS LIGHTSPEED Wireless Gaming Mouse with HERO 25K Sensor - Black - Front_Zoom
    Top comment

    "The 'Don of Mice...The Logitech G502 X PLUS LIGHTSPEED Wireless RGB Gaming Mouse definitely isn't. In fact, Logitech keep stepping up their game, making me state their latest, the Logitech G502 X PLUS LIGHTSPEED Wireless RGB Gaming Mouse, is the best mouse I've ever use. ...Great mouse...Great mouse if your wanting the functionality of more buttons than typical gaming mice. "

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    Product Description

    G502 X PLUS, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Also equipped with LIGHTSYNC RGB powering flowing 8-LED lighting that’s customizable and adapts as you play with startup/power-down effects and battery optimization through active play detection. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor and more.
    See all Gaming Mice
    Top comment

    "The 'Don of Mice...The Logitech G502 X PLUS LIGHTSPEED Wireless RGB Gaming Mouse definitely isn't. In fact, Logitech keep stepping up their game, making me state their latest, the Logitech G502 X PLUS LIGHTSPEED Wireless RGB Gaming Mouse, is the best mouse I've ever use. ...Great mouse...Great mouse if your wanting the functionality of more buttons than typical gaming mice. "

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    Product Description

    G502 X PLUS, the latest version of Logitech’s most popular gaming mouse, combines a legacy of performance with the most advanced gaming technologies. G502 X also introduces hybrid optical-mechanical LIGHTFORCE switches for the primary left and right buttons. Also equipped with LIGHTSYNC RGB powering flowing 8-LED lighting that’s customizable and adapts as you play with startup/power-down effects and battery optimization through active play detection. Complete with updated LIGHTSPEED wireless with 68 percent faster response rate, HERO 25K sub-micron sensor and more.
    See all Gaming Mice
    See all Gaming Mice
  10. ASUS - TUF Gaming A16 16" 165Hz Gaming Laptop FHD-AMD Ryzen 7 7735HS with 16GB DDR5 Memory- Radeon RX7600S 512GB PCIe SSD - OFF BLACK - Front_Zoom
    Top comment

    "Likely ok for most people as majority of people are right handed, but if you're a lefty, i can see you being annoyed. ...The ASUS TUF Gamin Laptop comes with a custom anodized aluminum finish in Sandstorm or Off-black colors certified to meet MIL-STD-810H specifications. It boasts Wi-Fi 6, Dolby Atmos Hi-Res Sound, AMD Radeon and AMD Ryzen Series 7000 componenets, a 165 hz refresh rate, 90% screen to body ratio, a MUX switch, High performance DDR5 RAM, Type C charging, 4 heat exhaust vents and 84 blade arc flow fans. "

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    Product Description

    ASUS TUF Gaming A16 Gaming Laptop gives you a durable and powerful, yet budget friendly gaming experience on Windows 11. The TUF Gaming A16 packs an 8-core AMD Ryzen 7 7735HS CPU and Radeon RX7600S V8G GPU into a thin gaming laptop. Enjoy a fast 165Hz refresh rate, 16GB of DDR5 RAM, and 512GB of SSD storage all wrapped in a light 4.85 lbs chassis. The future is powerful and long-lasting.
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    Top comment

    "Likely ok for most people as majority of people are right handed, but if you're a lefty, i can see you being annoyed. ...The ASUS TUF Gamin Laptop comes with a custom anodized aluminum finish in Sandstorm or Off-black colors certified to meet MIL-STD-810H specifications. It boasts Wi-Fi 6, Dolby Atmos Hi-Res Sound, AMD Radeon and AMD Ryzen Series 7000 componenets, a 165 hz refresh rate, 90% screen to body ratio, a MUX switch, High performance DDR5 RAM, Type C charging, 4 heat exhaust vents and 84 blade arc flow fans. "

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    Product Description

    ASUS TUF Gaming A16 Gaming Laptop gives you a durable and powerful, yet budget friendly gaming experience on Windows 11. The TUF Gaming A16 packs an 8-core AMD Ryzen 7 7735HS CPU and Radeon RX7600S V8G GPU into a thin gaming laptop. Enjoy a fast 165Hz refresh rate, 16GB of DDR5 RAM, and 512GB of SSD storage all wrapped in a light 4.85 lbs chassis. The future is powerful and long-lasting.
    See all Gaming Laptops
    See all Gaming Laptops
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