A:Answer 1. Not necessary, since it is just a monitor. It is preferred to get a desktop with a Nvidia video card. Since the monitor offers G-Sync that requires a Nvidia video card to use the feature. It also provides a refresh rate of 144hz, 160hz, 170hz,180hz option through a DP port connection. However, HDMI only supports 60hz.
2. Yes, if your motherboard or video card outputs has a HDMI port or DP port to operate it. Typically any computer can operate a monitor if it is connected to its ports.