A:Answeryou got to check if your motherboard supports ddr4 because that's what these rams are, if your motherboard only supports ddr3 then no they wont fit. I would recommend upgrading your motherboard to a ROG B550 f gaming motherboard that's what I got with my 32 Gb of vengeance ram
A:AnswerNot very well. That motherboard only supports RAM speeds of up to 2933 MHz (https://pcpartpicker.com/product/ZDGnTW/msi-b460m-pro-vdh-micro-atx-lga1200-motherboard-b460m-pro-vdh), and depending on which CPU you have it could be even lower. You could put the RAM in but it would be seriously bottlenecked.
A:AnswerMemory does not effect in game performance much, however 16GB is the golden standard of game performance and multitasking. More memory is helpful if you want to open 20 chrome tabs at once but while you can bottleneck with not enough memory or slow memory especially on Ryzen systems if you're seeking better FPS look into your CPU or GPU as places to upgrade.