A:Answer I have pretty large hands, which is why I had the Proteus core for so long before upgrading to this. Even with big hands, I can comfortably palm grip this one, and not have to claw grip it. (You certainly can if that's more comfortable to you, however.) On a rough measurement, looks like the mouse is around 5 1/4 inches or so. It's pretty large sized compared to many I've used in the past. I personally wouldn't have bought it if it were small, as I dislike that style of mouse.