A:Answer Thank you for asking. No, it won't work as this is not a factory pen replacement for any Wacom tablet in general lines. This pen is a stand alone device for selected 2in1 Windows devices.
The original pen replacement for your Bamboo Splash tablet was the LP170 pen (also the LP160 and LP180 could be used). Unfortunately these were discontinued some time ago.
That said, you may still be able to find those quoted pen models through some online vendors, else you may consider an upgrade of tablet as well. Hope that helps. Best