Best answer: Nope, this will fit with any case. The screen protector is fairly thin but works really, really well. No smudge marks unless you are purposely trying. I use a UAG case which is known for extremely snug and tight fitments. No issues. Also, I have used an otter box defender case and have had zero issues period. HOWEVER, I DO NOT an otter box defender case with this particular screen protector on it, especially if you like the high quality screen. The protector does not diminish image quality, however, adding the otter box screen to it definitely diminishes quality. If you still decide on the defender, remove the screen protector from the case and just use the privacy guard on it.
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